Acute Upper Gastrointestinal Bleeding in Elderly Persons

Acute Upper Gastrointestinal Bleeding in Elderly Persons
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老年人急性上消化道出血

DOI:
10.1111/j.1532-5415.1991.tb02911.x
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发表时间:
1991
影响因子:
6.3
通讯作者:
G. Ireland
G. Ireland
中科院分区:
医学1区
文献类型:
--
作者:
Douglas K. Miller;F. Burton;Mary S. Burton;G. Ireland

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我们已经看到,UGI出血是老年人面临的一个严重且明显日益严重的问题。在老年患者中特别值得关注的是严重消化性疾病静默出现的频率,非甾体抗炎药对充分缓解疼痛的限制,以及大多数UGI出血原因的较高并发症发生率。通过重点研究哪些老年患者最有可能出现非类固醇抗炎药引起的消化性并发症,改进耐受性好且成本效益高的预防或治疗非类固醇抗炎药引起的溃疡的方法,以及更好地预防这些患者的溃疡复发和UGI出血,将加强对老年人的护理。至于最后,未来对幽门螺杆菌作用的调查,成功根除这种微生物的方法,以及根除对患者后续病程的影响,可能特别有帮助。
We have seen that UGI bleeding is a serious and apparently growing problem for seniors. Of special concern in the older patient are the frequency with which serious peptic disease presents silently, the limitation frequently imposed on adequate pain relief from NSAIDs, and the higher complication rates from most of the causes of UGI bleeding. Care of the elderly would be enhanced by research focused on defining those older patients most at risk of experiencing NSAID-induced peptic complications, improved methods for preventing or treating NSAID-induced ulceration that are well tolerated and cost-effective, and better regimens for preventing the recurrence of ulcers and UGI bleeding in these patients. In regard to the last, future investigation of the role of H. pylori, methods for successfully eliminating the organism, and the effect of eradication on patients' subsequent course may be particularly helpful.
DOI: 10.1093/infdis/157.4.777
发表时间: 1988-04-01
影响因子: 6.4
作者:
GRAHAM, DY;KLEIN, PD;BOUTTON, TW
通讯作者: BOUTTON, TW
溃疡流行病学:概述和拟议的研究框架。
DOI: 10.1016/s0016-5085(89)80052-6
发表时间: 1989
期刊: Gastroenterology
影响因子: 29.4
作者:
Kurata,JH
通讯作者: Kurata,JH
消化性溃疡的发病机制及其对治疗的影响。
DOI: 10.1056/nejm199003293221307
发表时间: 1990
期刊: The New England journal of medicine
影响因子: --
作者:
Soll,AH
通讯作者: Soll,AH