Is there a general factor of prevalent psychopathology during adulthood?
Is there a general factor of prevalent psychopathology during adulthood?
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DOI：
10.1037/a0028355
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发表时间：
2012-11
影响因子：
4.6
通讯作者：
Rathouz, Paul J.
中科院分区：
文献类型：
--
作者：
Lahey, Benjamin B.;Applegate, Brooks;Hakes, Jahn K.;Zald, David H.;Hariri, Ahmad R.;Rathouz, Paul J.
成年人中流行的精神障碍的共病模式导致他们加载在“外化”，“痛苦”和“恐惧”因素。这些因素本身是强相关的，但很少有人注意到这一事实。作为第一步，在研究这些因素间的相关性的影响，验证性因素分析进行诊断的11个流行的DSM-IV精神障碍的全国代表性样本。一个模型指定相关的外部化，痛苦和恐惧因素适合，但另一种模型进行了测试，其中添加了一个“一般”的双因素，以捕捉这些疾病的共同点。有一个温和的，但显着的改善，适合双因素模型相对于3因素斜模型，所有疾病的负荷强烈的双因素。外部效度测试显示，恐惧，痛苦和外部因素与功能和潜在风险因素的措施有差异。尽管如此，一般双因素在未来的精神病理学，功能和其他标准中占了显着的独立方差，超过了恐惧，痛苦和外部因素。这些发现支持了这样一个假设，即这些流行的精神病理学形式既有重要的共同特征，也有独特的特征。未来的研究应该确定这是否是因为它们的病因和神经生物学机制相同。如果是这样的话，不同形式的流行精神病理学之间存在的共同特征可能对理解精神病理学的性质，病因和结果具有重要意义。
The patterns of comorbidity among prevalent mental disorders in adults lead them to load on ‘externalizing,’ ‘distress,’ and ‘fears’ factors. These factors are themselves robustly correlated, but little attention has been paid to this fact. As a first step in studying the implications of these inter-factor correlations, confirmatory factor analyses were conducted on diagnoses of 11 prevalent DSM-IV mental disorders in a nationally representative sample. A model specifying correlated externalizing, distress, and fears factors fit well, but an alternative model was tested in which a ‘general’ bifactor was added to capture what these disorders share in common. There was a modest but significant improvement in fit for the bifactor model relative to the 3-factor oblique model, with all disorders loading strongly on the bifactor. Tests of external validity revealed that the fears, distress, and externalizing factors were differentially associated with measures of functioning and potential risk factors. Nonetheless, the general bifactor accounted for significant independent variance in future psychopathology, functioning, and other criteria over and above the fears, distress, and externalizing factors. These findings support the hypothesis that these prevalent forms of psychopathology have both important common and unique features. Future studies should determine if this is because they share elements of their etiology and neurobiological mechanisms. If so, the existence of common features across diverse forms of prevalent psychopathology could have important implications for understanding the nature, etiology, and outcomes of psychopathology.
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DOI：
10.1111/j.1469-7610.2008.01981.x
发表时间：
2009-01-01
影响因子：
7.6
作者：
Angold, Adrian;Costello, E. Jane
通讯作者：
Costello, E. Jane
DOI：
10.1176/appi.ajp.2010.10030340
发表时间：
2011-01
期刊：
The American journal of psychiatry
影响因子：
--
作者：
Kendler KS;Aggen SH;Knudsen GP;Røysamb E;Neale MC;Reichborn-Kjennerud T
通讯作者：
Reichborn-Kjennerud T
影响因子：
3
作者：
GIBBONS, RD;HEDEKER, DR
通讯作者：
HEDEKER, DR
DOI：
10.1111/j.1467-8721.2007.00521.x
发表时间：
2007-10-01
影响因子：
7.2
作者：
Kovas, Yulia;Plomin, Robert
通讯作者：
Plomin, Robert
影响因子：
--
作者：
Grant, BF;Stinson, FS;Anderson, K
通讯作者：
Anderson, K