Mental Stress-Induced Myocardial Ischemia.
Mental Stress-Induced Myocardial Ischemia.
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DOI:
10.1007/s11886-022-01821-2
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发表时间:
2022-12
影响因子:
3.7
通讯作者:
Vaccarino, Viola
中科院分区:
文献类型:
--
作者:
Mehta, Puja K.;Sharma, Ashish;Bremner, J. Douglas;Vaccarino, Viola
To summarize recent evidence on mental stress-induced myocardial ischemia (MSIMI), its mechanisms, and clinical significance. MSIMI can occur in patients with normal cardiac stress testing, is only weakly related to severity of coronary artery disease (CAD), and it is often silent. Among patients with CAD, MSIMI is associated with a twofold increased risk of major adverse cardiovascular events compared to those who do not have MSIMI. Certain groups such as young women with myocardial infarction and those with psychological comorbidities are more susceptible to MSIMI. Abnormal microvascular vasoreactivity and inflammation are implicated mechanisms in MSIMI. Increased brain activity in regions that modulate autonomic reactivity to emotional stress and fear is associated with MSIMI. MSIMI has important prognostic implications in patients with CAD. Stress can no longer be ignored as a risk factor in cardiology care. Clinical trials testing effective strategies to target MSIMI are needed.
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影响因子:
24
作者:
Cho L;Davis M;Elgendy I;Epps K;Lindley KJ;Mehta PK;Michos ED;Minissian M;Pepine C;Vaccarino V;Volgman AS;ACC CVD Womens Committee Members
通讯作者:
ACC CVD Womens Committee Members
影响因子:
9.3
作者:
Bucciarelli V;Nasi M;Bianco F;Seferovic J;Ivkovic V;Gallina S;Mattioli AV
通讯作者:
Mattioli AV
DOI:
10.3389/fgwh.2021.606833
发表时间:
2021
期刊:
Frontiers in global women's health
影响因子:
--
作者:
Dhaibar HA;Cruz-Topete D
通讯作者:
Cruz-Topete D
DOI:
10.1097/nmd.0000000000001100
发表时间:
2020-03
期刊:
The Journal of nervous and mental disease
影响因子:
--
作者:
Bremner JD;Wittbrodt MT;Shah AJ;Pearce BD;Gurel NZ;Inan OT;Raggi P;Lewis TT;Quyyumi AA;Vaccarino V
通讯作者:
Vaccarino V
影响因子:
5.7
作者:
Arri, S. S.;Ryan, M.;Marber, M. S.
通讯作者:
Marber, M. S.