Atypical object exploration at 12 months of age is associated with autism in a prospective sample.
Atypical object exploration at 12 months of age is associated with autism in a prospective sample.
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DOI：
10.1177/1362361308096402
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发表时间：
2008-09
期刊：
影响因子：
--
通讯作者：
Rogers SJ
中科院分区：
文献类型：
--
作者：
Ozonoff S;Macari S;Young GS;Goldring S;Thompson M;Rogers SJ
这项前瞻性研究调查了66名12个月大的婴儿的物体探索行为，其中9名随后被诊断为自闭症谱系障碍。以前的研究对自闭症的重复行为特征何时首次出现在早期发展中存在分歧。一项任务的开发，提供了一系列重复使用的对象的具体机会，并编码盲目的结果状态。自闭症/ASD的结果组显示出显着更多的旋转，旋转，不寻常的视觉探索的对象比两个对照组。自闭症/ASD组的平均异常视觉探索评分比该组的平均值高出4个标准差以上，结果没有问题。12个月时的重复行为与36个月时的认知和症状状态显著相关。这些结果表明，重复或刻板的行为可能比最初认为的更早出现在发展自闭症表型的非常年幼的儿童中。
This prospective study examined object exploration behavior in 66 12-month-old infants, of whom nine were subsequently diagnosed with an autism spectrum disorder. Previous investigations differ on when the repetitive behaviors characteristic of autism are first present in early development. A task was developed that afforded specific opportunities for a range of repetitive uses of objects and was coded blind to outcome status. The autism/ASD outcome group displayed significantly more spinning, rotating, and unusual visual exploration of objects than two comparison groups. The average unusual visual exploration score of the autism/ASD group was over four standard deviations above the mean of the group with no concerns at outcome. Repetitive behaviors at 12 months were significantly related to cognitive and symptomatic status at 36 month outcome. These results suggest that repetitive or stereotyped behaviors may be present earlier than initially thought in very young children developing the autism phenotype.
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DOI：
10.1111/j.1469-7610.2007.01762.x
发表时间：
2007-09-01
影响因子：
7.6
作者：
Corsello, Christina;Hus, Vanessa;Lord, Catherine
通讯作者：
Lord, Catherine
DOI：
10.1097/00004703-200604002-00003
发表时间：
2006-04-01
影响因子：
2.4
作者：
Palomo, Ruben;Belinchon Carmona, Mercedes;Ozonoff, Sally
通讯作者：
Ozonoff, Sally
影响因子：
3.9
作者：
Richler, Jennifer;Bishop, Somer L.;Lord, Catherine
通讯作者：
Lord, Catherine
影响因子：
3.9
作者：
Lord, C;Risi, S;Rutter, M
通讯作者：
Rutter, M
影响因子：
2.5
作者：
THELEN, E
通讯作者：
THELEN, E