Effect of Manufacturing Process on the Biocompatibility and Mechanical Properties of Ti-30Ta Alloy.
Effect of Manufacturing Process on the Biocompatibility and Mechanical Properties of Ti-30Ta Alloy.
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DOI：
10.1007/s11665-011-9874-7
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发表时间：
2011-07-01
影响因子：
2.3
通讯作者：
Haider, W.
中科院分区：
文献类型：
--
作者：
Gill, P.;Munroe, N.;Pulletikurthi, C.;Pandya, S.;Haider, W.
钛合金以其高强度/重量比和耐腐蚀性而广泛应用于航空航天、化学和生物医学行业。然而，镍钛诺在后一个行业的使用一直充满了植入物释放镍的过敏和毒性作用的担忧。最近，无镍钛钽合金的开发受到了广泛关注，该合金被认为是金属对金属椎间盘置换、骨科植入物、心血管支架、牙桩和导丝等应用的主要候选者。在这项研究中，研究了通过粉末冶金（PM）和电弧熔炼（ARC）制造的Ti-30Ta合金的生物相容性。每种合金的耐腐蚀性根据 ASTM F 2129-08 在磷酸盐缓冲盐水 (PBS) 和含氨基酸的 PBS 中于 37 °C 测定。通过电感耦合等离子体质谱 (ICP-MS) 测量腐蚀过程中释放的金属离子浓度。使用扫描电子显微镜（SEM）评估腐蚀前后合金的形态。进行维氏硬度测试来比较合金的硬度和拉伸强度。人类成骨细胞在两种合金的表面成功生长。
Ti alloys have been widely used in the aerospace, chemical, and biomedical industries for their high strength/weight ratio and corrosion resistance. However, Nitinol’s usage in the latter industry has been fraught with concerns of allergic and toxic effects of Ni released from implants. Recently, much attention has been placed on the development of Ni-free Ti-Ta alloys, which are considered prime candidates for applications such as metal-on-metal spinal disk replacements, orthopedic implants, cardiovascular stents, dental posts, and guide wires. In this research, the biocompatibility of Ti-30Ta alloys manufactured by powder metallurgy (PM) and arc melting (ARC) were investigated. The corrosion resistance of each alloy was determined in accordance with ASTM F 2129-08 in phosphate buffered saline (PBS) and PBS with amino acids at 37 °C. The concentration of metal ions released during corrosion was measured by Inductively Coupled Plasma Mass Spectroscopy (ICP-MS). Scanning Electron Microscopy (SEM) was used to assess the morphology of the alloys before and after corrosion. Vicker’s hardness tests were performed to compare the hardness and tensile strength of the alloys. Human osteoblast cells were successfully grown on the surface of both alloys.
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影响因子：
9.7
作者：
Oliveira, N. T. C.;Guastaldi, A. C.
通讯作者：
Guastaldi, A. C.
DOI：
10.1002/jbm.b.31647
发表时间：
2010-08-01
影响因子：
3.4
作者：
Pound, Bruce G.
通讯作者：
Pound, Bruce G.
DOI：
10.1016/j.msec.2009.05.001
发表时间：
2009-08-31
影响因子：
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作者：
Tercero, Jorge E.;Namin, Shabnam;Agarwal, Arvind
通讯作者：
Agarwal, Arvind
DOI：
10.1023/a:1011210101895
发表时间：
2001-04-01
影响因子：
3.7
作者：
Trillo, EA;Ortiz, C;Murr, LE
通讯作者：
Murr, LE
影响因子：
14
作者：
Khan, MA;Williams, RL;Williams, DF
通讯作者：
Williams, DF