Case report of metastatic breast cancer mimicking ileal Crohn's disease.
Case report of metastatic breast cancer mimicking ileal Crohn's disease.
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DOI：
10.1016/j.ijscr.2021.106408
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发表时间：
2021-10
影响因子：
0.6
通讯作者：
Naraynsingh V
中科院分区：
文献类型：
--
作者：
Maharajh S;Capildeo K;Barrow M;Islam S;Naraynsingh V
与乳腺导管癌相比，小叶乳腺癌（LBC）的胃肠道（GI）扩散风险增加。乳腺癌通常转移到骨、肺、肝、中枢神经系统，很少转移到胃肠道。随着现代医学实践的发展，乳腺癌的预后不断改善，重要的是要了解乳腺癌转移的各种临床表现和适当的管理。我们描述了一个60岁的妇女谁提出的症状肠梗阻30个月后接受乳房切除术和辅助化疗的LBC。计算机断层扫描（CT）显示末端回肠增厚，提示克罗恩病，但组织病理学显示转移性小叶癌。手术切除以解除她的小肠梗阻证实LBC。这个病例说明了一个不寻常的介绍转移性乳腺癌引起小肠梗阻的放射学特征模仿克罗恩病。乳腺癌患者可因转移性扩散至小肠而出现肠梗阻;这在临床和放射学上可能类似于克罗恩病。乳腺癌是一种常见的恶性肿瘤。乳腺癌转移在放射学上可以表现为克罗恩病。在乳腺癌胃肠道扩散的病例中，内镜活检可能无法诊断。
Lobular breast cancer (LBC) has an increased risk of gastrointestinal (GI) spread compared with ductal breast carcinoma. Breast cancer commonly metastasises to bone, lung, liver, central nervous system and rarely to the gastrointestinal tract. As the prognosis for breast cancer continues to improve with modern medical practice it is important to be aware of the various clinical presentations and the appropriate management of breast cancer metastases. We describe a case of a 60-year-old woman who presented with symptoms of bowel obstruction 30 months after undergoing mastectomy and adjuvant chemotherapy for LBC. A Computer Tomography (CT) scan showed terminal ileal thickening suggestive of Crohn's disease but histopathology revealed metastatic lobular carcinoma. Surgical resection to relieve her small bowel obstruction confirmed LBC. This case illustrates an unusual presentation of metastatic breast cancer causing small bowel obstruction with radiological features mimicking Crohn's disease. Patients with breast cancer can present with intestinal obstruction due to metastatic spread to the small intestine; this may resemble Crohn's disease clinically and radiologically. Lobular breast cancer is more likely to metastasize to the gastrointestinal tract. Breast cancer metastases can appear radiologically as Crohn’s disease. Endoscopic biopsies in cases of GI spread of breast cancer can be nondiagnostic.
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