Genetic diversity, population structure and Wolbachia infection status in a worldwide sample of Drosophila melanogaster and D. simulans populations.
Genetic diversity, population structure and Wolbachia infection status in a worldwide sample of Drosophila melanogaster and D. simulans populations.
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DOI：
10.1371/journal.pone.0026318
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发表时间：
2011
期刊：
影响因子：
3.7
通讯作者：
Haddrill PR
中科院分区：
文献类型：
--
作者：
Verspoor RL;Haddrill PR
在种群遗传模型的发展中，果蝇及其近亲一直是极其重要的模式物种，该模型用于解释自然种群的多样性模式，这是进化生物学的主要目标。随着包括人口变化和自然选择在内的各种力量的相对重要性得到确立，这些物种的进化史的详细图景开始浮出水面。一个持续的目标是描述这些物种大量种群的遗传多样性水平，覆盖广泛的地理区域。我们使用了来自三个大洲的五个以前未采样的黑腹金龟子野生种群和两个金龟子野生种群的样本。我们估计了这些种群内的遗传多样性水平以及它们之间的差异，并寻找祖先和派生种群之间以及派生种群之间遗传结构的证据。我们还调查了细菌内共生菌沃尔巴克氏菌的感染情况。我们发现，来自撒哈拉以南非洲的黑腹金龟子种群是最多样化的，这些种群与非撒哈拉以南非洲种群之间的差异最大。有强有力的证据表明撒哈拉以南非洲和世界其他地区之间的人口结构，也有一些证据表明派生人口的结构较弱。撒哈拉以南非洲的人群在沃尔巴克氏菌感染的流行程度上也不同，与世界其他地区的人群相比，感染水平非常低。
Drosophila melanogaster and its close relatives have been extremely important model species in the development of population genetic models that serve to explain patterns of diversity in natural populations, a major goal of evolutionary biology. A detailed picture of the evolutionary history of these species is beginning to emerge, as the relative importance of forces including demographic changes and natural selection is established. A continuing aim is to characterise levels of genetic diversity in a large number of populations of these species, covering a wide geographic area. We have used collections from five previously un-sampled wild populations of D. melanogaster and two of D. simulans, across three continents. We estimated levels of genetic diversity within, and divergence between, these populations, and looked for evidence of genetic structure both between ancestral and derived populations, and amongst derived populations. We also investigated the prevalence of infection with the bacterial endosymbiont Wolbachia. We found that D. melanogaster populations from Sub-Saharan Africa are the most diverse, and that divergence is highest between these and non-Sub-Saharan populations. There is strong evidence for structuring of populations between Sub-Saharan Africa and the rest of the world, and some evidence for weak structure amongst derived populations. Populations from Sub-Saharan Africa also differ in the prevalence of Wolbachia infection, with very low levels of infection compared to populations from the rest of the world.
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影响因子：
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