Chaperoning ribosome assembly.
Chaperoning ribosome assembly.
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DOI:
10.1083/jcb.201002102
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发表时间:
2010-04-05
期刊:
影响因子:
--
通讯作者:
Karbstein K
中科院分区:
文献类型:
--
作者:
Karbstein K
Chaperones help proteins fold in all cellular compartments, and many associate directly with ribosomes, capturing nascent chains to assist their folding and prevent aggregation. In this issue, new data from Koplin et al. (2010. J. Cell Biol. doi: 10.1083/jcb.200910074) and Albanèse et al. (2010. J. Cell Biol. doi: 10.1083/jcb.201001054) suggest that in addition to promoting protein folding, the chaperones ribosome-associated complex (RAC), nascent chain–associated complex (NAC), and Jjj1 also help in the assembly of ribosomes.
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