Review of Preterm Human-Milk Nutrient Composition.

Review of Preterm Human-Milk Nutrient Composition.
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回顾早产的人乳营养成分。

DOI:
10.1002/ncp.10570
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发表时间:
2021-12
期刊:
Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition
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母乳喂养的早产儿有生长障碍、微量营养素缺乏和神经认知发育迟缓的风险。虽然母乳比配方奶具有更好的保护性和耐受性,但单独的母乳不能满足这一人群的高营养需求,因此有必要进行强化。临床医生使用早产儿母乳成分的假设来确定强化的类型和数量。本综述的目的是确定早产母乳中常量营养素和微量营养素浓度的证据,并确定有关成分的知识差距。PubMed和护理和相关健康文献累积索引用于识别1950年1月至2019年12月期间发表的原始文章。发现27篇文章包含大量营养素和微量营养素的原始数据。2011年之后发表的大多数(67%)研究测量了大量营养素,包括28至36周的胎龄。不同研究的乳汁采集方法、实验设计和分析方法各不相同。有15个国家的代表在这次审查;所有的美国研究(n = 7)发表于1980年至1984年。非裔美国妇女或妊娠28周前分娩的妇女未在文献中出现。准确和有针对性的人乳营养强化取决于全面、完整和具有代表性的人乳营养数据。我们汇总了所有可用的早产母乳常量营养素和微量营养素数据,并报告了与哺乳期和胎龄相关的趋势。这份报告可以帮助设计适合早产儿胎龄和母乳泌乳阶段的喂养计划。
The human milk–fed preterm infant is at risk for growth failure, micronutrient deficiencies, and neurocognitive delay. Although protective and better tolerated than formula, human milk alone cannot meet the high nutrient requirements of this population, and fortification is necessary. Clinicians use assumptions of preterm human-milk composition to determine the type and quantity of fortification. The objectives of this review were to identify evidence of macronutrient and micronutrient concentration in preterm human milk and to identify knowledge gaps regarding composition. PubMed and the Cumulative Index to Nursing and Allied Health Literature were used to identify original articles published between January 1950 and December 2019. Twenty-seven articles were found containing original data on macronutrients and micronutrients. Most (67%) of the studies published after 2011 measured the macronutrients and included gestational ages from 28 to 36 weeks. Milk collection methods, experimental design, and analytical methods varied between studies. There are 15 countries represented in this review; all of the American studies (n = 7) were published from 1980 to 1984. African American women, or women delivering before 28 weeks’ gestation are not represented in the literature. Accurate and targeted human-milk fortification depends on comprehensive, complete, and representative human-milk nutrient data. We have aggregated all available preterm human-milk macronutrient and micronutrient data and reported trends associated with lactation stage and gestational age. This report can aid in the design of feeding plans that are appropriate for the gestational age of the preterm infant and the lactation stage of the breastmilk.
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影响因子: 5.9
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