The clinical and behavioral cardiometabolic risk of children and young people on mental health inpatient units: A systematic review and meta-analysis.

The clinical and behavioral cardiometabolic risk of children and young people on mental health inpatient units: A systematic review and meta-analysis.
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DOI:
10.1016/j.genhosppsych.2021.03.007
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发表时间:
2021-05
影响因子:
7
通讯作者:
Lovell K
Lovell K
中科院分区:
医学2区
文献类型:
--
作者:
Carney R;Firth J;Pedley R;Law H;Parker S;Lovell K

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严重的精神疾病与身体健康共病有关,但大多数研究都集中在成年人身上。我们的目的是综合现有文献的临床和行为的心脏代谢危险因素的年轻人的精神卫生住院单位。采用电子检索PsycINFO、EMBASE、AMED、科克伦对照试验中心注册中心和奥维德MEDLINE进行系统综述和荟萃分析。合格的研究包括儿童/青少年精神卫生住院单位<25岁,报告临床/行为心脏代谢危险因素。包含成人样本、病例研究或进食障碍人群的研究被排除在外。主要的临床结果是体重,主要的行为结果是烟草使用。确定了39项研究(n = 809,185)。超重(BMI > 25)的年轻人合并患病率为32.4%(95%CI 26.1%-39.5%; n = 2789),肥胖(BMI > 30)的年轻人合并患病率为15.5%(95%CI 4.5%-41.6%; n = 2612)。烟草使用的合并患病率为51.5%(95% CI 32.2-70.2; N = 804,018)。观察到代谢风险的早期迹象;血胆固醇升高,存在身体健康状况和行为风险因素(例如缺乏体力活动)。这次审查强调了住院的年轻人的脆弱性,并强调有机会有效地监测,治疗和干预,以达到身心健康的目标。
Serious mental illness is associated with physical health comorbidities, however most research has focused on adults. We aimed to synthesise existing literature on clinical and behavioral cardiometabolic risk factors of young people on mental health inpatient units. A systematic review and meta-analysis was conducted, using electronic searches of PsycINFO, EMBASE, AMED, Cochrane Central Register of Controlled Trials, and Ovid MEDLINE. Eligible studies included child/adolescent mental health inpatient units for <25 years, reporting clinical/behavioral cardiometabolic risk factors. Studies containing adult samples, case-studies, or eating disorder populations were excluded. The main clinical outcome was weight, and main behavioral outcome was tobacco use. Thirty-nine studies were identified (n = 809,185). Pooled prevalence rates of young people who were overweight (BMI > 25) was 32.4% (95% CI 26.1%–39.5%; n = 2789), and who were obese (BMI > 30) was 15.5% (95% CI 4.5%–41.6%; n = 2612). Pooled prevalence rates for tobacco use was 51.5% (95% CI 32.2–70.2; N = 804,018). Early signs of metabolic risk were observed; elevated blood cholesterol, presence of physical health conditions, and behavioral risk factors (e.g. physical inactivity). This review highlights the vulnerability of young people admitted to inpatient units and emphasises the opportunity to efficiently monitor, treat and intervene to target physical and mental health.
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