Developmental and evolutionary basis for drought tolerance of the Anopheles gambiae embryo.
Developmental and evolutionary basis for drought tolerance of the Anopheles gambiae embryo.
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DOI：
10.1016/j.ydbio.2009.02.038
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发表时间：
2009-06-15
影响因子：
2.7
通讯作者：
Levine, Michael
中科院分区：
文献类型：
--
作者：
Goltsev, Yury;Rezende, Gustavo L.;Vranizan, Karen;Lanzaro, Greg;Valle, Denise;Levine, Michael
关键词：
在双翅目进化过程中，胚胎外胚层发生了巨大的改变，蚊子含有独立的羊膜和浆膜谱系，而高等果蝇如黑腹果蝇则含有单一的羊膜浆膜。对冈比亚疟原虫胚胎中分离的浆膜进行全基因组转录组测定。这些测定鉴定出大量与幼虫角质层的产生有关的基因。在黑腹果蝇中，这些基因在胚胎发生过程中仅被激活一次，在后期用于幼虫角质层的产生。有证据表明，浆膜细胞分泌一种专用的浆膜角质层，可以保护冈比亚疟原虫胚胎免于干燥。蚊子基因表达谱的详细时间微阵列分析表明，角质层基因在冈比亚蚊胚胎发生过程中表现出双相表达，首先在早期胚胎的浆膜中，然后在晚期阶段再次表达，如黑腹蚊中所见。我们讨论了明确的背腹模式网络的进化修饰如何导致冈比亚早期胚胎中角质层生物合成途径的大规模部署。
During the evolution of the Diptera there is a dramatic modification of the embryonic ectoderm, whereby mosquitoes contain separate amnion and serosa lineages while higher flies such as D. melanogaster contain a single amnioserosa. Whole-genome transcriptome assays were performed with isolated serosa from A. gambiae embryos. These assays identified a large number of genes implicated in the production of the larval cuticle. In D. melanogaster, these genes are activated just once during embryogenesis, during late stages where they are used for the production of the larval cuticle. Evidence is presented that the serosal cells secrete a dedicated serosal cuticle, which protects A. gambiae embryos from desiccation. Detailed temporal microarray assays of mosquito gene expression profiles revealed that the cuticular genes display biphasic expression during A. gambiae embryogenesis, first in the serosa of early embryos and then again during late stages as seen in D. melanogaster. We discuss how evolutionary modifications in the well-defined dorsal-ventral patterning network led to the wholesale deployment of the cuticle biosynthesis pathway in early embryos of A. gambiae.
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DOI：
10.4269/ajtmh.2005.73.553
发表时间：
2005-09-01
影响因子：
3.3
作者：
Gray, EM;Bradley, TJ
通讯作者：
Bradley, TJ
DOI：
10.1111/j.2517-6161.1995.tb02031.x
发表时间：
1995-01-01
影响因子：
5.8
作者：
BENJAMINI, Y;HOCHBERG, Y
通讯作者：
HOCHBERG, Y
影响因子：
4.1
作者：
Gilbert, LI
通讯作者：
Gilbert, LI
DOI：
10.1139/z58-050
发表时间：
1958-01-01
期刊：
CANADIAN JOUR ZOOL
影响因子：
--
作者：
BECKEL, W. E.
通讯作者：
BECKEL, W. E.
影响因子：
4.6
作者：
Goltsev, Yury;Fuse, Naoyuki;Levine, Mike
通讯作者：
Levine, Mike