PLEXdb: gene expression resources for plants and plant pathogens.

PLEXdb: gene expression resources for plants and plant pathogens.
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DOI:
10.1093/nar/gkr938
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发表时间:
2012-01
影响因子:
14.9
通讯作者:
Dickerson JA
Dickerson JA
中科院分区:
生物学2区
文献类型:
--
作者:
Dash S;Van Hemert J;Hong L;Wise RP;Dickerson JA

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PLEXDB(http://www.plexdb.org),与社区数据库合作,支持比较多种植物和病原体物种的基因表达,促进个人和/或联合体上传基因组规模的数据集,将其与以前存档的数据进行对比。这些分析有助于解释经济作物中基因的结构、功能和调控。一份基因图谱实验清单重点介绍了给出不同发育阶段、条件和组织反应的数据集。PLEXdb的工具使用户能够快速、轻松地执行复杂的分析。模式基因组询问器(MGI)工具支持将基因列表映射到包括水稻和拟南芥在内的模式植物生物的相应基因上。MGI预测同源性,显示基因结构和注释基因和全长cDNA的支持信息。基因列表处理向导通过PLEXdb函数引导用户创建、分析、注释和管理基因列表。用户可以上传他们自己的列表或根据PLEXdb工具的输出创建它们,然后应用各种更高级别的分析,如方差分析和聚类分析。PLEXdb还为用户提供了使用基因示波器跟踪许多不同实验中基因表达变化的方法。这个工具可以识别有趣的表达模式,例如在不同条件下上调或检查任何基因作为稳定对照的适用性。
PLEXdb (http://www.plexdb.org), in partnership with community databases, supports comparisons of gene expression across multiple plant and pathogen species, promoting individuals and/or consortia to upload genome-scale data sets to contrast them to previously archived data. These analyses facilitate the interpretation of structure, function and regulation of genes in economically important plants. A list of Gene Atlas experiments highlights data sets that give responses across different developmental stages, conditions and tissues. Tools at PLEXdb allow users to perform complex analyses quickly and easily. The Model Genome Interrogator (MGI) tool supports mapping gene lists onto corresponding genes from model plant organisms, including rice and Arabidopsis. MGI predicts homologies, displays gene structures and supporting information for annotated genes and full-length cDNAs. The gene list-processing wizard guides users through PLEXdb functions for creating, analyzing, annotating and managing gene lists. Users can upload their own lists or create them from the output of PLEXdb tools, and then apply diverse higher level analyses, such as ANOVA and clustering. PLEXdb also provides methods for users to track how gene expression changes across many different experiments using the Gene OscilloScope. This tool can identify interesting expression patterns, such as up-regulation under diverse conditions or checking any gene’s suitability as a steady-state control.
拟南芥信息资源(TAIR):基因结构和功能注释。
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