Impact of COVID-19 on anxiety levels among patients with cancer actively treated with systemic therapy.
Impact of COVID-19 on anxiety levels among patients with cancer actively treated with systemic therapy.
复制标题
COVID-19对接受全身治疗的癌症患者的焦虑水平的影响。
DOI：
10.1136/esmoopen-2020-000970
复制
发表时间：
2020-10
期刊：
影响因子：
7.3
通讯作者：
Bodnar L
中科院分区：
文献类型：
--
作者：
Sigorski D;Sobczuk P;Osmola M;Kuć K;Walerzak A;Wilk M;Ciszewski T;Kopeć S;Hryń K;Rutkowski P;Stec R;Szczylik C;Bodnar L
危及生命的疾病对情绪健康和心理社会功能有负面影响。这项研究旨在评估在新冠肺炎大流行期间积极接受系统治疗的癌症患者中，肿瘤引起的焦虑水平与冠状病毒感染威胁之间的关系。此外，我们还寻找与更高水平的焦虑相关的临床因素。在波兰进行的这项多中心、前瞻性、非干预性研究中，我们招募了306名积极治疗的癌症患者，并收集了他们的临床数据，包括年龄、性别、癌症类型和治疗意图。采用新冠肺炎恐惧量表(SRA-FCV-19S)和数字焦虑量表(SRA-NAS)对SARS-CoV-2患者进行恐惧/焦虑评定。癌症相关恐惧和焦虑(CRA)用NAS(CRA-NAS)进行评定。血清sRA-FCV-19s平均水平为18.5±7.44s，与sRA-nas呈正相关(r=0.741，P<0.001)。女性的SRA-FCV-19s显著高于男性(20.18±7.56vs16.54±6.83vsp<；0.001)，且与肿瘤类型有关(p=0.037)，乳腺癌患者焦虑程度最高(17.63vs8.75)。在多变量分析中，只有女性与较高的SRA显著相关。女性患者的CRA-NAS高于男性(7.07±2.99vs5.47±3.01；p<；0.001)；接受根治性或姑息性治疗的患者(7.14±3.06vs5.99±3.06；p=0.007)；65岁的≤患者(6.73±2.96vs5.66±3.24；p=0.007)。对于一名积极接受治疗的癌症患者来说，在新冠肺炎大流行期间，癌症仍然是威胁生命的主要疾病。应特别为女性患者、乳腺癌患者、65岁以下有治疗意向的患者提供更细心的心理护理，因为这些因素与较高水平的焦虑有关。
Life-threatening diseases have a negative impact on emotional well-being and psychosocial functioning. This study aimed to assess the relationship between the level of anxiety caused by a neoplasm and the threat of coronavirus infection among patients with cancer actively treated with systemic therapy during the COVID-19 pandemic. Additionally, we searched for clinical factors associated with a higher level of anxiety. In this multicentre, prospective, non-interventional study conducted in Poland, we enrolled 306 actively treated patients with cancer and collected their clinical data, including age, gender, cancer type and treatment intention. The fear/anxiety of SARS-CoV-2 were rated in Fear of COVID-19 Scale (SRA-FCV-19S) and Numerical Anxiety Scale (SRA-NAS). The fear and anxiety associated with cancer (CRA) were rated with the NAS (CRA-NAS). The mean level of SRA-FCV-19S was 18.5±7.44, which was correlated with the SRA-NAS (r=0.741, p<0.001). SRA-FCV-19S was significantly higher in women versus men (20.18±7.56 vs 16.54±6.83; p<0.001) and was tumour type-dependent (p=0.037), with the highest anxiety observed in patients with breast cancer (17.63±8.75). In the multivariate analysis, only the female gender was significantly associated with higher SRA. CRA-NAS was higher in women versus men (7.07±2.99 vs 5.47±3.01; p<0.001), in patients treated with curative versus palliative intention (7.14±3.06 vs 5.99±3.06; p=0.01) and in individuals aged ≤65 years versus >65 years (6.73±2.96 vs 5.66±3.24; p=0.007). For an actively treated patient with cancer, cancer remains the main life-threatening disease during the COVID-19 pandemic. The need for more attentive psychological care should be provided especially to female patients, patients with breast cancer, those under 65 years of age and treated with curative intention, as these factors are associated with a higher level of anxiety.
登录
查看更多内容
DOI：
10.5114/wo.2015.54900
发表时间：
2015
期刊：
Contemporary oncology (Poznan, Poland)
影响因子：
--
作者：
Czerw AI;Marek E;Deptała A
通讯作者：
Deptała A
影响因子：
11.3
作者：
Cao, Wenjun;Fang, Ziwei;Zheng, Jianzhong
通讯作者：
Zheng, Jianzhong
影响因子：
4.2
作者：
Classen, C;Koopman, C;Spiegel, D
通讯作者：
Spiegel, D
影响因子：
51.1
作者：
Garassino, Marina Chiara;Whisenant, Jennifer G.;Horn, Leora
通讯作者：
Horn, Leora
影响因子：
6.8
作者：
Fu, Wenning;Wang, Chao;Mao, Jing
通讯作者：
Mao, Jing