Perceived stress predicts allergy flares.

Perceived stress predicts allergy flares.
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感知的压力可以预测过敏性耀斑。

DOI:
10.1016/j.anai.2013.07.013
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发表时间:
2014-04
影响因子:
5.9
通讯作者:
Malarkey, William B.
Malarkey, William B.
中科院分区:
医学2区
文献类型:
--
作者:
Patterson, Amber M.;Yildiz, Vedat O.;Klatt, Maryanna D.;Malarkey, William B.

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压力与鼻炎症状之间的关系尚未确定。为了确定参与者报告的过敏反应是否与感知的情绪压力、抑郁、情绪和压力的生物标记物(皮质醇)相关。这项研究是对179名大学员工的二次分析,他们参与了一项研究,评估了几种生活方式干预对健康症状和炎症的影响。在每两周的研究前进行压力感知和抑郁症状问卷调查。在线日记记录了当天的过敏症发作、应激事件、感觉到的压力、情绪和唾液皮质醇水平,在2个14天的块中每天收集。39%的受试者(n=69)自我报告过敏症状。与没有过敏症状的那组相比,这组过敏性闪光组有更高的感知压力得分。在两个独立的14天期间,感觉到的压力,而不是抑郁症状,与过敏性症状评估呈正相关。在研究过程中,负面情绪评分与过敏症状之间也存在正相关。皮质醇与过敏症状发作无关。这些发现表明,有持续情绪压力的人有更频繁的过敏症发作。此外,那些拥有更多耀斑的人有更多的负面情绪。
A relation between stress and symptoms of rhinitis has not been established. To determine if participants’ reporting of allergy flares correlated with perceived emotional stress, depression, mood, and a biomarker of stress (cortisol). This study was a secondary analysis of 179 university employees who participated in a study evaluating the influence of several lifestyle interventions on health symptoms and inflammation. Perceived stress and depressive symptom questionnaires were obtained before each 2-week study period. Online diary entries documenting same-day allergy flares, stressful events, perceived stress, mood, and salivary cortisol levels were collected daily during 2 14-day blocks. Thirty-nine percent of subjects (n = 69) self-reported allergy symptoms. This allergy flare group had higher perceived stress scores than the group without allergy symptoms. Perceived stress, but not depressive symptoms, positively correlated with allergy flares evaluated during 2 independent 14-day periods. There also was a positive relation between negative mood scores and allergy flares over the course of the study. Cortisol had no association with allergy symptom flares. These findings suggest that individuals with persistent emotional stress have more frequent allergy flares. Furthermore, those with more flares have greater negative mood.
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