DichroMatch at the protein circular dichroism data bank (DM@PCDDB): A web-based tool for identifying protein nearest neighbors using circular dichroism spectroscopy.

DichroMatch at the protein circular dichroism data bank (DM@PCDDB): A web-based tool for identifying protein nearest neighbors using circular dichroism spectroscopy.
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DOI:
10.1002/pro.3207
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发表时间:
2018-01
期刊:
Protein science : a publication of the Protein Society
影响因子:
--
通讯作者:
Janes RW
Janes RW
中科院分区:
其他
文献类型:
--
作者:
Whitmore L;Mavridis L;Wallace BA;Janes RW

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圆二色谱是结构生物学中一种常用但简单的方法,用于提供蛋白质二级结构和折叠的信息。DichroMatch(DM@PCDDB)是蛋白质圆二色性数据库(PCDDB)中新提供的在线工具,其利用其中存储的丰富的光谱和元数据,基于四种不同的光谱匹配方法来识别查询蛋白质的光谱最近邻。DM@PCDDB可以潜在地提供关于蛋白质之间的结构关系的新信息,并且可以用于蛋白质同源物和直系同源物的比较研究。
Circular dichroism spectroscopy is a well‐used, but simple method in structural biology for providing information on the secondary structure and folds of proteins. DichroMatch (DM@PCDDB) is an online tool that is newly available in the Protein Circular Dichroism Data Bank (PCDDB), which takes advantage of the wealth of spectral and metadata deposited therein, to enable identification of spectral nearest neighbors of a query protein based on four different methods of spectral matching. DM@PCDDB can potentially provide novel information about structural relationships between proteins and can be used in comparison studies of protein homologs and orthologs.
DOI: 10.1093/nar/gkw796
发表时间: 2017-01-04
影响因子: 14.9
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Whitmore L;Miles AJ;Mavridis L;Janes RW;Wallace BA
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