PCDDB: new developments at the Protein Circular Dichroism Data Bank.

PCDDB: new developments at the Protein Circular Dichroism Data Bank.
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DOI:
10.1093/nar/gkw796
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发表时间:
2017-01-04
影响因子:
14.9
通讯作者:
Wallace BA
Wallace BA
中科院分区:
生物学2区
文献类型:
--
作者:
Whitmore L;Miles AJ;Mavridis L;Janes RW;Wallace BA

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蛋白质圆二色性数据库(PCDDB)已经运行了5年多,作为存档圆二色性光谱数据和相关生物信息学和实验元数据的公共存储库。自其诞生以来,在数据显示、搜索算法、数据格式、数据内容、辅助信息和验证技术方面都有了许多改进和新的发展,当然,持有量也有所增加。它提供了一个网站(pcddb.cryst.bbk.ac.uk)供作者存款实验数据以及与已发表工作相关的方法和计算的详细信息。它还包括每个条目到生物信息学数据库的链接。这些数据可以作为单个文件或完整的数据库下载免费提供给访问者。PCDDB已被结构生物学、生物信息学、分析和制药界广泛使用,并已成为新软件和方法开发的基础。
The Protein Circular Dichroism Data Bank (PCDDB) has been in operation for more than 5 years as a public repository for archiving circular dichroism spectroscopic data and associated bioinformatics and experimental metadata. Since its inception, many improvements and new developments have been made in data display, searching algorithms, data formats, data content, auxillary information, and validation techniques, as well as, of course, an increase in the number of holdings. It provides a site (http://pcddb.cryst.bbk.ac.uk) for authors to deposit experimental data as well as detailed information on methods and calculations associated with published work. It also includes links for each entry to bioinformatics databases. The data are freely available to accessors either as single files or as complete data bank downloads. The PCDDB has found broad usage by the structural biology, bioinformatics, analytical and pharmaceutical communities, and has formed the basis for new software and methods developments.
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