Determinants of COVID-19 vaccine preference: A survey study in Japan.

Determinants of COVID-19 vaccine preference: A survey study in Japan.
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COVID-19疫苗偏好的决定因素:日本的一项调查研究。

DOI:
10.1016/j.ssmph.2021.100902
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发表时间:
2021-09
期刊:
SSM - population health
影响因子:
--
通讯作者:
Nakabayashi M
Nakabayashi M
中科院分区:
其他
文献类型:
--
作者:
Kawata K;Nakabayashi M

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接种疫苗是遏制新冠肺炎大流行的关键措施。我们调查了影响日本对新冠肺炎疫苗偏好的决定因素,日本是一个对疫苗犹豫不决的国家。我们通过招募15,000名日本成年人的非概率样本,对互联网上的疫苗偏好进行了一项随机联合分析调查。调查向受访者分配了5项选择任务。在每项任务中,受访者评估了2种假想的新冠肺炎疫苗,并被问及会选择哪种。疫苗属性包括疗效、主要和次要副作用、疫苗开发和临床试验的国家以及疫苗类型。选择任务要求参与者从两种假设疫苗中选择一种作为可选疫苗,或者按照要求选择一种疫苗,每种疫苗的概率为0.5。与中国研发的疫苗相比,国产或美国研发的疫苗分别使选择概率提高了37.3和27.4个百分点。一项国内临床试验使选择概率增加了14.8,有效率从50%提高到90%,增加了18.0,严重不良反应的风险从1/1万下降到1/100万,分别增加了16.9个百分点。疫苗类型无关紧要。强制接种疫苗使中国和俄罗斯开发的疫苗的选择概率分别增加了0.6%和0.4%,高危疫苗增加了0.5%,中等有效(70%)疫苗的选择概率增加了0.4%。普遍的疫苗接种犹豫不决、政治立场、人口统计特征、教育程度和收入都不相关。国内开发的具有国内临床试验的疫苗可能会大大增加人们对疫苗的偏好。强制接种疫苗可以适度减少对具有不良副作用、地缘政治和疗效问题的疫苗的惩罚,可能是通过缓解搭便车问题来实现群体免疫。我们进行了新冠肺炎疫苗偏好的随机联合实验。我们询问了15,000名日本成年人,在两种假想疫苗中选择哪一种。作为一种治疗,我们随机分配了自愿和强制接种疫苗的情景。国内开发和临床试验基本上是首选。强制接种疫苗略微提高了人们对风险更高的疫苗的偏好。
Vaccination is a critical measure for containing the COVID-19 pandemic. We survey the determinants that affect the preference for COVID-19 vaccines in Japan, a vaccine hesitant nation. We conducted a randomized conjoint analysis survey of the preference for vaccines on the Internet by recruiting a nonprobability sample of 15,000 Japanese adults. The survey assigned 5 choice tasks to the respondents. In each task, the respondents evaluated 2 hypothetical COVID-19 vaccines and were asked which they would choose. The vaccine attributes included efficacy, major and minor adverse side effects, country of vaccine development and clinical trial, and vaccine type. The choice task asked the participants to select a vaccine from 2 hypothetical vaccines as an optional vaccine or select a vaccine as mandated one with a probability of 0.5 for each. Compared to China-developed vaccines, domestically developed or US-developed vaccines raised the choice probability by 37.3 and 27.4 percentage points, respectively. A domestic clinical trial increased the choice probability by 14.8, an increase in efficacy from 50% to 90% increased that by 18.0, and a decrease in the risk of severe adverse side effects from 1 per 10 thousand to 1 per 1 million increased that by 16.9 percentage points, respectively. The vaccine type was irrelevant. Making vaccination compulsory increased the choice probability of China- and Russia-developed vaccines by 0.6 and 0.4, high-risk vaccines by 0.5, and a modestly effective (70%) vaccine by 0.4 percentage points, respectively. General vaccination hesitancy, political positions, demographic characteristics, education, and income were irrelevant. A domestically developed vaccine with a domestic clinical trial could substantially increase the preference for the vaccine. Making vaccination compulsory could modestly reduce the penalty for a vaccine with adverse side effects, geopolitical, and efficacy concerns, possibly through mitigating free-riding concerns to achieve herd immunity. We implement a randomized conjoint experiment on preference of COVID-19 vaccines. We asked 15,000 Japanese adults which to prefer between two hypothetical vaccines. As a treatment, we randomly assigned voluntary and compulsory vaccination scenarios. Domestic development and clinical trial were substantially preferred. Compulsory vaccination modestly raised preference for riskier vaccines.
DOI: 10.1016/s2468-2667(21)00012-8
发表时间: 2021-04
期刊: The Lancet. Public health
影响因子: --
作者:
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