Home-based exercise during preoperative therapy for pancreatic cancer.
Home-based exercise during preoperative therapy for pancreatic cancer.
复制标题
DOI：
10.1007/s00423-017-1599-0
复制
发表时间：
2017-12
期刊：
影响因子：
--
通讯作者：
Katz MHG
中科院分区：
文献类型：
--
作者：
Ngo-Huang A;Parker NH;Wang X;Petzel MQB;Fogelman D;Schadler KL;Bruera E;Fleming JB;Lee JE;Katz MHG
Exercise concurrent with neoadjuvant chemotherapy and/or chemoradiation for pancreatic adenocarcinoma (PDAC) may mitigate the decline in function that may occur as a result of the disease or its treatment in the preoperative period. The primary objective of this single-arm prospective trial was to determine adherence to a home-based exercise program administered during preoperative therapy. Twenty patients from a quaternary cancer center with potentially resectable PDAC were enrolled. Patients were prescribed a minimum of 120 minutes of moderate-intensity exercise weekly: at least 60 minutes of aerobic exercise and 60 minutes of resistance exercise. Self-reported exercise was recorded in daily logs. Functional and survey measures were collected upon enrollment, following preoperative therapy, and 1 month after surgery. Fifteen out of twenty patients participated in the program. They reported a mean (standard deviation [SD]) of 98.6 (69.8) minutes of aerobic exercise weekly and 57.4 (36.0) minutes of strengthening exercise weekly over a median of 17 weeks (range, 5–35 weeks) of preoperative therapy, for a mean (SD) of 156.0 (64.5) minutes of total exercise weekly. 80% reported a mean of least 120 minutes of total exercise weekly during preoperative therapy. Patients with low baseline physical activity based on the International Physical Activity Questionnaire significantly increased their preoperative physical activity (p =.01). There were no adverse events associated with the exercise program. Patients with PDAC will participate in a home-based exercise program of aerobic and strengthening exercise, and will increase physical activity, concurrent with preoperative chemotherapy and/or chemoradiation.
登录
查看更多内容
影响因子：
3.7
作者：
Cooper, Amanda B.;Slack, Rebecca;Katz, Matthew H. G.
通讯作者：
Katz, Matthew H. G.
DOI：
10.1136/bmj.b5631
发表时间：
2010-01-19
期刊：
BMJ (Clinical research ed.)
影响因子：
--
作者：
Dalal HM;Zawada A;Jolly K;Moxham T;Taylor RS
通讯作者：
Taylor RS
影响因子：
0.7
作者：
Bohannon, Richard W.;Shove, Megan E.;Sigouin, Christopher S.
通讯作者：
Sigouin, Christopher S.
影响因子：
6.7
作者：
Bohannon, RW
通讯作者：
Bohannon, RW
影响因子：
4.7
作者：
Cheville, Andrea L.;Kollasch, Jenny;Basford, Jeffrey R.
通讯作者：
Basford, Jeffrey R.