Cardiac motion in diffusion-weighted MRI of the liver: artifact and a method of correction.

Cardiac motion in diffusion-weighted MRI of the liver: artifact and a method of correction.
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DOI:
10.1002/jmri.22816
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发表时间:
2012-02
影响因子:
4.4
通讯作者:
Bydder, Mark
Bydder, Mark
中科院分区:
医学2区
文献类型:
--
作者:
Liau, Joy;Lee, Jimmy;Schroeder, Michael E.;Sirlin, Claude B.;Bydder, Mark

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To characterize cardiac motion artifacts in the liver and assess the use of a post-processing method to mitigate these artifacts in repeat measurements. Three subjects underwent breathhold diffusion-weighted (DW) scans consisting of 25 repetitions for three b-values (0, 500, 1000 sec/mm2). Statistical maps computed from these repetitions were used to assess the distribution and behavior of cardiac motion artifacts in the liver. An objective post-processing method to reduce the artifacts were compared with radiologist-defined gold standards. Signal dropout is pronounced in areas proximal to the heart, such as the left lobe, but also present in the right lobe and in distal liver segments. The dropout worsens with b-value and leads to overestimation of the diffusivity. By reference to a radiologist-defined gold standard, a post-processing correction method is shown to reduce cardiac motion artifact. Cardiac motion leads to significant artifacts in liver DW imaging; we propose a post-processing method that may be used to mitigate the artifact and is advantageous to standard signal averaging in acquisitions with multiple repetitions.
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