Electroacupuncture and cognitive behavioural therapy for sub-syndromal depression among undergraduates: a controlled clinical trial.
Electroacupuncture and cognitive behavioural therapy for sub-syndromal depression among undergraduates: a controlled clinical trial.
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DOI：
10.1136/acupmed-2015-010981
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发表时间：
2016-10
期刊：
影响因子：
--
通讯作者：
Ya T
中科院分区：
文献类型：
--
作者：
Guo T;Guo Z;Zhang W;Ma W;Yang X;Yang X;Hwang J;He X;Chen X;Ya T
亚综合征抑郁(SSD)患者发生抑郁障碍的风险增加；然而，SSD的理想治疗方法仍不清楚。目的：评价电针(EA)和认知行为疗法(CBT)单独或联合治疗抑郁症状的疗效。将患有SSD的大学生根据他们的喜好分为四组：电针组(n=6)、CBT组(n=10)、电针+CBT组(n=6)和未处理对照组(n=11)。前三组均接受为期六周的治疗。采用17项汉密尔顿抑郁量表(HAMD-17)、流行病学抑郁中心(CES-D)量表、WHO生活质量简明版(WHOQOL-BREF)问卷和临床缓解率来评估临床结果。所有33名受试者都被纳入意向治疗分析。与对照组相比，电针、CBT和电针+CBT干预组的HAMD-17、CES-D和WHOQOL-BREF评分均有显著改善，缓解率更高(均P<0.05)。三个干预组之间无显著差异。HAMD-17因子分分析显示，电针对睡眠障碍评分的降低作用大于CBT或电针+CBT(p<；0.05)，CBT对迟缓评分的降低作用大于电针(p<；0.01)。电针+CBT比电针或CBT降低焦虑/躯体化评分更多(p<；0.05)，迟缓评分比电针更多(p<；0.05)。早期干预可能会缓解SSD的抑郁症状。电针和CBT对某些症状可能有不同的疗效。针对躯体和心理症状的联合治疗可能是SSD干预的理想策略。然而，需要进行样本量更大的随机试验。CHICCTR-TRC-10000889；结果。
Individuals with sub-syndromal depression (SSD) are at increased risk of incident depressive disorders; however, the ideal therapeutic approach to SSD remains unknown. To evaluate the effects of electroacupuncture (EA) and cognitive behavioural therapy (CBT), alone or in combination, on depressive symptoms. Undergraduate students with SSD were recruited and allocated to one of four groups based on their preferences: EA (n=6), CBT (n=10), EA+CBT (n=6), and untreated control (n=11) groups. Six weeks of treatment were provided in the first three groups. Clinical outcomes were measured using the 17-item Hamilton Depression (HAMD-17) rating scale, Center for Epidemiologic Depression (CES-D) scale, WHO Quality of Life-Brief version (WHOQOL-BREF) questionnaire, and clinical remission rate. All 33 subjects were included in an intent-to-treat analysis. Statistically significant improvements in HAMD-17, CES-D, and WHOQOL-BREF scores and a higher remission rate were found in the EA, CBT, and EA+CBT intervention groups compared with the control group (all p<0.05). No significant differences were found between the three intervention groups. HAMD-17 factor score analysis revealed that EA reduced sleep disturbance scores more than CBT or EA+CBT (p<0.05), and CBT reduced retardation scores more than EA (p<0.01). EA+CBT reduced anxiety/somatisation scores more than EA or CBT (p<0.05) and retardation scores more than EA (p<0.05). Early intervention may alleviate depressive symptoms in SSD. EA and CBT may have differential effects on certain symptoms. Combination therapy targeting both physical and psychological symptoms may represent an ideal strategy for SSD intervention. However, randomised trials with larger sample sizes are needed. ChiCTR-TRC-10000889; Results.
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影响因子：
3.7
作者：
Johansson R;Sjöberg E;Sjögren M;Johnsson E;Carlbring P;Andersson T;Rousseau A;Andersson G
通讯作者：
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作者：
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