A protective effect of lithium on rat behaviour altered by ibotenic acid lesions of the basal forebrain cholinergic system
A protective effect of lithium on rat behaviour altered by ibotenic acid lesions of the basal forebrain cholinergic system
复制标题
锂对因鹅膏菌酸损伤基底前脑胆碱能系统而改变的大鼠行为的保护作用
DOI:
10.1016/0006-8993(95)00934-g
复制
发表时间:
1995
期刊:
影响因子:
2.9
通讯作者:
Jose
中科院分区:
文献类型:
--
作者:
T. Pascual;Jose
Lithium was tested on an animal model of a brain cholinergic excitotoxic lesion. Male Wistar rats received unilaterally 50 nmol ibotenic acid in the nucleus basalis magnocellularis. Some were treated intraperitoneally with LiCl from two days before to six days after lesioning. Such treated rats showed less deficits than untreated lesioned animals on passive avoidance, ambulatory behaviour and choline acetyltransferase activity in the lesioned cortex. Lithium protection against excitatory amino acid neurotoxicity is suggested.
影响因子:
1.9
作者:
Wenk,GL;Harrington,CA;Tucker,DA;Rance,NE;Walker,LC
通讯作者:
Walker,LC
DOI:
10.1016/s0021-9258(19)70391-3
发表时间:
1980-11
期刊:
The Journal of biological chemistry
影响因子:
--
作者:
Loretta M. HallcherS;W. Sherman
通讯作者:
Loretta M. HallcherS;W. Sherman
DOI:
10.1056/nejm199409013310907
发表时间:
1994-09
期刊:
The New England journal of medicine
影响因子:
--
作者:
L. Price;G. Heninger
通讯作者:
L. Price;G. Heninger