Thirtieth Anniversary of the Discovery of Laxaphycins. Intriguing Peptides Keeping a Part of Their Mystery.

Thirtieth Anniversary of the Discovery of Laxaphycins. Intriguing Peptides Keeping a Part of Their Mystery.
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DOI:
10.3390/md19090473
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发表时间:
2021-08-24
期刊:
影响因子:
5.4
通讯作者:
Inguimbert N
Inguimbert N
中科院分区:
医学2区
文献类型:
--
作者:
Darcel L;Das S;Bonnard I;Banaigs B;Inguimbert N

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脂肽是一类通常由微生物通过涉及非核糖体肽合酶和聚酮基合酶的杂合生物合成途径产生的化合物。蓝细菌产生的laxaphycins是这个家族的化合物,在过去的三十年中已经扩大的例子。这些化合物受益于技术进步,有助于其合成和表征,以及破译其生物合成。本文试图总结大部分的文章,已发表的laxaphycins。目前的知识,这些复杂的化合物的生态作用也将进行审查。
Lipopeptides are a class of compounds generally produced by microorganisms through hybrid biosynthetic pathways involving non-ribosomal peptide synthase and a polyketyl synthase. Cyanobacterial-produced laxaphycins are examples of this family of compounds that have expanded over the past three decades. These compounds benefit from technological advances helping in their synthesis and characterization, as well as in deciphering their biosynthesis. The present article attempts to summarize most of the articles that have been published on laxaphycins. The current knowledge on the ecological role of these complex sets of compounds will also be examined.
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发表时间: 2020-06-01
影响因子: 2.9
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