Stress-induced obesity and the emotional nervous system.

Stress-induced obesity and the emotional nervous system.
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DOI:
10.1016/j.tem.2009.10.004
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发表时间:
2010-03
影响因子:
10.9
通讯作者:
Dallman, Mary F.
Dallman, Mary F.
中科院分区:
医学1区
文献类型:
--
作者:
Dallman, Mary F.

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压力和情绪化的大脑网络促进了可能导致肥胖的饮食行为。神经网络是压力源、身体、大脑和食物摄入之间复杂相互作用的基础,现在已经得到了更好的理解。应激源通过激活神经应激反应网络,使认知偏向于增加情绪活动和降低执行功能。这导致形成的习惯被使用,而不是对反应的认知评估。压力也会引起糖皮质激素和胰岛素的分泌,糖皮质激素会增加食物的动力,胰岛素会促进食物摄入和肥胖。愉快的进食减少了压力反应网络的活动,加强了进食习惯。压力源的这些影响强调了教授心理重新评估技术的重要性,以恢复从习惯到深思熟虑的反应,从而对抗压力引起的肥胖。
Stress and emotional brain networks foster eating behaviors that may lead to obesity. The neural networks underlying the complex interactions among stressors, body, brain and food intake are now better understood. Stressors, by activating a neural stress-response network, bias cognition toward increased emotional activity and degraded executive function. This causes formed habits to be used rather than a cognitive appraisal of responses. Stress also induces secretion of both glucocorticoids, which increases motivation for food, and insulin, which promotes food intake and obesity. Pleasurable feeding then reduces activity in the stress-response network, reinforcing the feeding habit. These effects of stressors emphasize the importance of teaching mental reappraisal techniques to restore responses from habitual to thoughtful, thus battling stress-induced obesity.
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期刊: Science (New York, N.Y.)
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