MassSieve: panning MS/MS peptide data for proteins.

MassSieve: panning MS/MS peptide data for proteins.
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DOI:
10.1002/pmic.200900370
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发表时间:
2010-08
期刊:
影响因子:
3.4
通讯作者:
Markey, Sanford P.
Markey, Sanford P.
中科院分区:
生物学3区
文献类型:
--
作者:
Slotta, Douglas J.;McFarland, Melinda A.;Markey, Sanford P.

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We present MassSieve, a Java-based platform for visualization and parsimony analysis of single and comparative LC-MS/MS database search engine results. The success of mass spectrometric peptide sequence assignment algorithms has led to the need for a tool to merge and evaluate the increasing data set sizes that result from LC-MS/MS-based shotgun proteomic experiments. MassSieve supports reports from multiple search engines with differing search characteristics, which can increase peptide sequence coverage and/or identify conflicting or ambiguous spectral assignments.
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