Functional diffusive/convective interaction determining maximal oxygen uptake in humans: its modeling perspective.

Functional diffusive/convective interaction determining maximal oxygen uptake in humans: its modeling perspective.
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功能扩散/对流相互作用决定人类最大摄氧量:其建模视角。

DOI:
10.2114/ahs.14.259
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发表时间:
1995
期刊:
Applied human science : journal of physiological anthropology
影响因子:
--
通讯作者:
H. Sato
H. Sato
中科院分区:
--
文献类型:
--
作者:
Y. Fukuba;A. Miura;A. Kan;K. Yanagawa;H. Sato

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在这篇简短的综述中,主要从建模角度总结了当前关于人类最大动态运动期间从环境空气到肌肉线粒体的氧气流量上限(即 VO2max)的决定因素的理解框架。在最近关于最大摄氧量限制因素的争论中反复出现的几种模型和实验证据被采用和批评。总之,VO2max 特别是由 O2 流路径中肺 O2 负荷和肌肉 O2 卸载的扩散因素和对流因素之间的综合相互作用决定,尽管目前无法令人满意地解释所有实验观察结果。
In this short review, the frame of current understandings concerning what determines the upper limit of oxygen flow from the ambient air to the muscular mitochondria during maximal dynamic exercise in humans (i.e., VO2max), was summarized mainly from its modeling perspective. Several models and experimental evidences which appeared repeatedly in the recent debates regarding the factors limiting VO2max, were adopted and criticized. In conclusion, VO2max is determined in particular by the integrated interaction between the diffusive and convective factors both to lung O2-loading and muscular O2-unloading in the pathway for O2 flow, although all experimental observations cannot be satisfactorily explained at the present time.
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