DIANA-TarBase v8: a decade-long collection of experimentally supported miRNA-gene interactions.
DIANA-TarBase v8: a decade-long collection of experimentally supported miRNA-gene interactions.
复制标题
DOI:
10.1093/nar/gkx1141
复制
发表时间:
2018-01-04
影响因子:
14.9
通讯作者:
Hatzigeorgiou AG
中科院分区:
文献类型:
--
作者:
Karagkouni D;Paraskevopoulou MD;Chatzopoulos S;Vlachos IS;Tastsoglou S;Kanellos I;Papadimitriou D;Kavakiotis I;Maniou S;Skoufos G;Vergoulis T;Dalamagas T;Hatzigeorgiou AG
DIANA-TarBase v8 (http://www.microrna.gr/tarbase) is a reference database devoted to the indexing of experimentally supported microRNA (miRNA) targets. Its eighth version is the first database indexing >1 million entries, corresponding to ∼670 000 unique miRNA-target pairs. The interactions are supported by >33 experimental methodologies, applied to ∼600 cell types/tissues under ∼451 experimental conditions. It integrates information on cell-type specific miRNA–gene regulation, while hundreds of thousands of miRNA-binding locations are reported. TarBase is coming of age, with more than a decade of continuous support in the non-coding RNA field. A new module has been implemented that enables the browsing of interactions through different filtering combinations. It permits easy retrieval of positive and negative miRNA targets per species, methodology, cell type and tissue. An incorporated ranking system is utilized for the display of interactions based on the robustness of their supporting methodologies. Statistics, pie-charts and interactive bar-plots depicting the database content are available through a dedicated result page. An intuitive interface is introduced, providing a user-friendly application with flexible options to different queries.
登录
查看更多内容
影响因子:
48
作者:
Huber W;Carey VJ;Gentleman R;Anders S;Carlson M;Carvalho BS;Bravo HC;Davis S;Gatto L;Girke T;Gottardo R;Hahne F;Hansen KD;Irizarry RA;Lawrence M;Love MI;MacDonald J;Obenchain V;Oleś AK;Pagès H;Reyes A;Shannon P;Smyth GK;Tenenbaum D;Waldron L;Morgan M
通讯作者:
Morgan M
影响因子:
14.9
作者:
Ritchie ME;Phipson B;Wu D;Hu Y;Law CW;Shi W;Smyth GK
通讯作者:
Smyth GK
影响因子:
14.9
作者:
Thomson DW;Bracken CP;Goodall GJ
通讯作者:
Goodall GJ
影响因子:
14.9
作者:
Kodama Y;Shumway M;Leinonen R;International Nucleotide Sequence Database Collaboration
通讯作者:
International Nucleotide Sequence Database Collaboration
影响因子:
14.9
作者:
Li JH;Liu S;Zhou H;Qu LH;Yang JH
通讯作者:
Yang JH