Psychiatric comorbidity and social adjustment difficulties in children with disruptive mood dysregulation disorder: A national epidemiological study.

Psychiatric comorbidity and social adjustment difficulties in children with disruptive mood dysregulation disorder: A national epidemiological study.
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DOI:
10.1016/j.jad.2020.12.039
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发表时间:
2021-02-15
影响因子:
6.6
通讯作者:
Gau SS
Gau SS
中科院分区:
医学2区
文献类型:
--
作者:
Lin YJ;Tseng WL;Gau SS

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背景我们从台湾的一项全国流行病学研究中检查了破坏性情绪失调障碍 (DMDD) 儿童的相关性、精神合并症和社会适应困难。方法样本包括 4816 名儿童,他们是根据最近的全国儿童精神障碍调查中的城市化水平随机选择的学校的三、五和七年级学生。在使用 DSM-5 情感障碍和精神分裂症表 (K-SADS-E) 的 Kiddie 流行病学版本 (K-SADS-E) 采访的 4816 名儿童(2520 名男孩,52.3%)中,30 名儿童被诊断为 DMDD(23 名男孩,76.7%)。他们和他们的父母还报告了儿童和青少年社会适应量表(SAICA)。我们对控制分层和聚类的调查数据进行回归。结果台湾儿童DMDD的加权患病率为0.3~0.76%。与没有 DMDD 的儿童相比,患有 DMDD 的儿童的父母教育水平较低、男性占主导地位、精神合并症较高、自我报告的学校功能较差(例如,与同龄人之间存在更多行为问题)。其他分析显示,对立违抗障碍 (ODD) 而不是 DMDD 与品行障碍相关。患有或不患有DMDD的ODD儿童比仅患有DMDD的儿童在学校态度、学习成绩和家庭亲子互动方面存在更多问题。局限性DMDD样本量小。结论DMDD是社区中的一种罕见疾病。患有 DMDD 的儿童比没有患有 DMDD 的儿童有更多的精神合并症,并且主观上经历了更多的困难。 DMDD 和 ODD 都在不同的领域造成了严重的损害。
BackgroundWe examined correlates, psychiatric comorbidities, and social adjustment difficulties in children with disruptive mood dysregulation disorder (DMDD) from a national epidemiological study in Taiwan.MethodsThe sample consisted of 4816 children, who were 3rd, 5th, and 7thgraders from schools randomly chosen based on the urbanization level in a recent national survey of childhood mental disorders. Among the 4816 children (2520 boys, 52.3%) interviewed using the Kiddie epidemiologic version of the Schedule for Affective Disorders and Schizophrenia (K-SADS-E) for the DSM-5, 30 children were diagnosed as DMDD (23 boys, 76.7%). They and their parents also reported on the Social Adjustment Inventory for Children and Adolescents (SAICA). We conducted regressions for survey data that controlled for stratification and clustering.ResultsThe weighted prevalence of DMDD was 0.3~0.76% in Taiwanese children. Lower parental educational levels, male predominance, higher psychiatric comorbidities, and worse self-report school functions (e.g., more behavioral problems with peers) were observed in children with DMDD than those without. Additional analyses revealed that oppositional defiant disorder (ODD) but not DMDD was related to conduct disorder. Children with ODD with or without DMDD had more problems regarding attitudes toward school, academic performance, and parent-child interaction at home than those with DMDD-only.LimitationsSmall sample size of DMDD.ConclusionsDMDD is a rare disorder in the community. Children with DMDD had more psychiatric comorbidities, and subjectively experienced more difficulties than those without. DMDD and ODD both resulted in severe impairment yet in different domains.
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