Genus Sophora: a comprehensive review on secondary chemical metabolites and their biological aspects from past achievements to future perspectives.

Genus Sophora: a comprehensive review on secondary chemical metabolites and their biological aspects from past achievements to future perspectives.
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DOI:
10.1007/s12272-021-01354-2
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发表时间:
2021-11
影响因子:
6.7
通讯作者:
Radwan MO
Radwan MO
中科院分区:
医学2区
文献类型:
--
作者:
Abd-Alla HI;Souguir D;Radwan MO

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槐属是豆科植物中最重要的属之一,也是开花植物中的第三大科。槐属植物约有52种、19变种和7变型,广泛分布于亚洲和非洲。槐属物种被认为是广谱生物活性次级代谢物的重要来源,即黄酮类化合物、黄酮类化合物、查耳酮、色酮、紫檀烷、香豆素、苯并呋喃衍生物、甾醇、皂苷(主要是三萜糖苷)、低聚芪,以及主要是生物碱。同时,槐属植物的提取物和分离的化合物已被鉴定具有几种有希望的健康作用,包括抗炎、抗关节炎、抗血小板、解热、抗癌、抗病毒、抗微生物、抗氧化、抗骨质疏松、抗溃疡性结肠炎、抗糖尿病、抗肥胖、抗疟疾和杀虫活性。本文就槐属植物的化学成分及其生物学效应进行综述。综述了从槐属植物中提取的植物营养素及其生物活性。该综述还澄清了剩余的差距,从而为这些化合物的进一步研究提供了一个平台。
Sophora is deemed as one of the most remarkable genera of Fabaceae, and the third largest family of flowering plants. The genus Sophora comprises approximately 52 species, 19 varieties, and 7 forms that are widely distributed in Asia and mildly in Africa. Sophora species are recognized to be substantial sources of broad spectrum biopertinent secondary metabolites namely flavonoids, isoflavonoids, chalcones, chromones, pterocarpans, coumarins, benzofuran derivatives, sterols, saponins (mainly triterpene glycosides), oligostilbenes, and mainly alkaloids. Meanwhile, extracts and isolated compounds from Sophora have been identified to possess several health-promising effects including anti-inflammatory, anti-arthritic, antiplatelets, antipyretic, anticancer, antiviral, antimicrobial, antioxidant, anti-osteoporosis, anti-ulcerative colitis, antidiabetic, anti-obesity, antidiarrheal, and insecticidal activities. Herein, the present review aims to provide comprehensive details about the phytochemicals and biological effects of Sophora species. The review spotlighted on the promising phytonutrients extracted from Sophora and their plethora of bioactivities. The review also clarifies the remaining gaps and thus qualifies and supplies a platform for further investigations of these compounds.
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