Prevalence and risk factors for epiretinal membranes in a multi-ethnic United States population.
Prevalence and risk factors for epiretinal membranes in a multi-ethnic United States population.
复制标题
DOI：
10.1016/j.ophtha.2010.08.009
复制
发表时间：
2011-04
期刊：
影响因子：
13.7
通讯作者：
Wong TY
中科院分区：
文献类型：
--
作者：
Ng CH;Cheung N;Wang JJ;Islam AF;Kawasaki R;Meuer SM;Cotch MF;Klein BE;Klein R;Wong TY
描述多种族人群中视网膜前膜（ERM）的患病率和风险因素，并评价可能的人种/种族差异。横断面研究。多种族动脉粥样硬化研究（梅萨）的参与者，在梅萨第二次访视时进行视网膜摄影检查。对来自梅萨的5960名年龄在45至84岁之间的参与者的数据进行了分析，其中包括来自美国六个社区的白色、黑人、西班牙裔和华人。ERM由数字非立体眼底照片评估，并定义为无视网膜褶皱的玻璃纸黄斑反射（CMR）或有视网膜褶皱的视网膜前黄斑纤维化（PMF）。通过标准化访谈、临床检查和实验室检查评估风险因素。按民族/种族群体划分的ERM患病率以及与ERM相关的风险因素。任何ERM的患病率为28.9%，其中25.1%为CMR，3.8%为PMF。与西班牙裔（29.3%）、白人（27.5%）和黑人（26.2%）相比，中国人（39.0%）的ERM患病率显著更高，p<0.001。在多变量模型中，年龄增加（比值比[OR] 1.19，95%置信区间[CI]，1.06，1.34，年龄每年增加）、糖尿病（OR 1.92，95% CI，1.39，2.65）和高胆固醇血症（OR 1.33，95% CI，1.04，1.69）与CMR显著相关。这项研究表明，与白人、黑人和西班牙裔相比，中国人的ERM明显更常见。视网膜前膜的危险因素是年龄增长、糖尿病和高胆固醇血症。
To describe the prevalence of and risk factors for epiretinal membrane (ERM) in a multi-ethnic population and to evaluate possible racial/ethnic differences. Cross-sectional study. Participants of the Multi-Ethnic Study of Atherosclerosis (MESA), examined at the second visit of the MESA when retinal photography was performed. Data on 5960 participants aged 45 to 84 years from MESA, including white, blacks, Hispanic and Chinese from six United States communities, were analysed. ERM was assessed from digital non-stereoscopic fundus photographs and defined as cellophane macular reflex (CMR) without retinal folds or pre-retinal macular fibrosis (PMF) with retinal folds. Risk factors were assessed from standardized interviews, clinical examinations, and laboratory investigations. ERM prevalence by ethnic/racial group, and risk factors associated with ERM. The prevalence of any ERM was 28.9%, of which 25.1% were CMR and 3.8% were PMF. The prevalence of ERM was significantly higher in Chinese (39.0%), compared to Hispanics (29.3%), whites (27.5%), and blacks (26.2%), p<0.001. In multivariable models, increasing age (odds ratio [OR] 1.19, 95% confidence intervals [CI], 1.06, 1.34, per year increase in age), diabetes (OR 1.92, 95% CI, 1.39, 2.65) and hypercholesterolemia (OR 1.33, 95% CI, 1.04, 1.69) were significantly associated with CMR. This study showed that ERM was significantly more common in Chinese persons compared to whites, blacks and Hispanics. Risk factors for epiretinal membrane were increasing age, presence of diabetes and hypercholesterolemia.
登录
查看更多内容
影响因子：
5
作者：
Nelson, J;Jiang, XC;Shea, S
通讯作者：
Shea, S
影响因子：
3.9
作者：
Kawasaki, R.;Wang, J. J.;Wong, T. Y.
通讯作者：
Wong, T. Y.
影响因子：
13.7
作者：
Klein, R;Klein, BEK;Jacobs, DR
通讯作者：
Jacobs, DR
影响因子：
3.9
作者：
You, Q.;Xu, L.;Jonas, J. B.
通讯作者：
Jonas, J. B.
影响因子：
4.4
作者：
Duan, Xin Rong;Liang, Yuan Bo;Wong, Tien Yin
通讯作者：
Wong, Tien Yin