WiggleTools: parallel processing of large collections of genome-wide datasets for visualization and statistical analysis.
WiggleTools: parallel processing of large collections of genome-wide datasets for visualization and statistical analysis.
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DOI:
10.1093/bioinformatics/btt737
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发表时间:
2014-04-01
期刊:
影响因子:
--
通讯作者:
Flicek P
中科院分区:
文献类型:
--
作者:
Zerbino DR;Johnson N;Juettemann T;Wilder SP;Flicek P
Motivation: Using high-throughput sequencing, researchers are now generating hundreds of whole-genome assays to measure various features such as transcription factor binding, histone marks, DNA methylation or RNA transcription. Displaying so much data generally leads to a confusing accumulation of plots. We describe here a multithreaded library that computes statistics on large numbers of datasets (Wiggle, BigWig, Bed, BigBed and BAM), generating statistical summaries within minutes with limited memory requirements, whether on the whole genome or on selected regions. Availability and Implementation: The code is freely available under Apache 2.0 license at www.github.com/Ensembl/Wiggletools Contact: zerbino@ebi.ac.uk or flicek@ebi.ac.uk
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DOI:
10.1093/bioinformatics/btq033
发表时间:
2010-03-15
期刊:
Bioinformatics (Oxford, England)
影响因子:
--
作者:
Quinlan AR;Hall IM
通讯作者:
Hall IM
影响因子:
14.9
作者:
Flicek P;Ahmed I;Amode MR;Barrell D;Beal K;Brent S;Carvalho-Silva D;Clapham P;Coates G;Fairley S;Fitzgerald S;Gil L;García-Girón C;Gordon L;Hourlier T;Hunt S;Juettemann T;Kähäri AK;Keenan S;Komorowska M;Kulesha E;Longden I;Maurel T;McLaren WM;Muffato M;Nag R;Overduin B;Pignatelli M;Pritchard B;Pritchard E;Riat HS;Ritchie GR;Ruffier M;Schuster M;Sheppard D;Sobral D;Taylor K;Thormann A;Trevanion S;White S;Wilder SP;Aken BL;Birney E;Cunningham F;Dunham I;Harrow J;Herrero J;Hubbard TJ;Johnson N;Kinsella R;Parker A;Spudich G;Yates A;Zadissa A;Searle SM
通讯作者:
Searle SM
影响因子:
14.9
作者:
Meyer LR;Zweig AS;Hinrichs AS;Karolchik D;Kuhn RM;Wong M;Sloan CA;Rosenbloom KR;Roe G;Rhead B;Raney BJ;Pohl A;Malladi VS;Li CH;Lee BT;Learned K;Kirkup V;Hsu F;Heitner S;Harte RA;Haeussler M;Guruvadoo L;Goldman M;Giardine BM;Fujita PA;Dreszer TR;Diekhans M;Cline MS;Clawson H;Barber GP;Haussler D;Kent WJ
通讯作者:
Kent WJ
影响因子:
46.9
作者:
Bernstein, Bradley E.;Stamatoyannopoulos, John A.;Costello, Joseph F.;Ren, Bing;Milosavljevic, Aleksandar;Meissner, Alexander;Kellis, Manolis;Marra, Marco A.;Beaudet, Arthur L.;Ecker, Joseph R.;Farnham, Peggy J.;Hirst, Martin;Lander, Eric S.;Mikkelsen, Tarjei S.;Thomson, James A.
通讯作者:
Thomson, James A.
DOI:
10.1093/bioinformatics/btp352
发表时间:
2009-08-15
期刊:
Bioinformatics (Oxford, England)
影响因子:
--
作者:
Li H;Handsaker B;Wysoker A;Fennell T;Ruan J;Homer N;Marth G;Abecasis G;Durbin R;1000 Genome Project Data Processing Subgroup
通讯作者:
1000 Genome Project Data Processing Subgroup