Differentiation of speech-induced artifacts from physiological high gamma activity in intracranial recordings.
Differentiation of speech-induced artifacts from physiological high gamma activity in intracranial recordings.
复制标题
语音诱导的伪影与颅内记录中生理高γ活性的分化。
DOI：
10.1016/j.neuroimage.2022.118962
复制
发表时间：
2022-04-15
期刊：
影响因子：
5.7
通讯作者：
Richardson RM
中科院分区：
文献类型：
--
作者：
Bush A;Chrabaszcz A;Peterson V;Saravanan V;Dastolfo-Hromack C;Lipski WJ;Richardson RM
人们对确定言语产生的神经生理学基础非常感兴趣。深部脑刺激(DBS)手术的独特之处在于，它允许在清醒和说话的患者中从皮质和皮质下区域进行颅内记录。然而，这些录音的质量可能会受到语音本身产生的机械力的不同程度的影响。在这里，我们描述了从标测电极、DBS导联和皮质电极获得的局域场电位(LFP)记录中语音诱导伪影的存在。除了预期在语音产生期间高伽马(60-200赫兹)活动的生理性增加外，许多通道的时频分析还显示出窄带伽马分量，其模式与在语音音频谱图中观察到的模式相似。这种成分在多种类型的神经记录中都有不同程度的存在。我们发现，该分量跟踪参与者语音的基频，与语音的功率谱相关，并与产生的语音音频具有一致性。安装在立体定向框架上的振动传感器记录了语音诱导的振动，其模式与LFP中观察到的模式相同。在音节重复任务的听时阶段，在任何神经通道中都没有发现相应的成分。这些观察表明，语音诱发的振动如何在感兴趣的主要频段产生伪像。识别和解释这些伪影对于确定DBS手术期间从颅内记录中获得的语音相关数据的有效性和可重复性至关重要。
There is great interest in identifying the neurophysiological underpinnings of speech production. Deep brain stimulation (DBS) surgery is unique in that it allows intracranial recordings from both cortical and subcortical regions in patients who are awake and speaking. The quality of these recordings, however, may be affected to various degrees by mechanical forces resulting from speech itself. Here we describe the presence of speech-induced artifacts in local-field potential (LFP) recordings obtained from mapping electrodes, DBS leads, and cortical electrodes. In addition to expected physiological increases in high gamma (60–200 Hz) activity during speech production, time-frequency analysis in many channels revealed a narrowband gamma component that exhibited a pattern similar to that observed in the speech audio spectrogram. This component was present to different degrees in multiple types of neural recordings. We show that this component tracks the fundamental frequency of the participant’s voice, correlates with the power spectrum of speech and has coherence with the produced speech audio. A vibration sensor attached to the stereotactic frame recorded speech-induced vibrations with the same pattern observed in the LFPs. No corresponding component was identified in any neural channel during the listening epoch of a syllable repetition task. These observations demonstrate how speech-induced vibrations can create artifacts in the primary frequency band of interest. Identifying and accounting for these artifacts is crucial for establishing the validity and reproducibility of speech-related data obtained from intracranial recordings during DBS surgery.
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DOI：
10.1073/pnas.1414491112
发表时间：
2015-03-03
影响因子：
11.1
作者：
Flinker, Adeen;Korzeniewska, Anna;Crone, Nathan E.
通讯作者：
Crone, Nathan E.
MEG揭示的对听觉频率遵循响应的皮质贡献。
影响因子：
16.6
作者：
Coffey EB;Herholz SC;Chepesiuk AM;Baillet S;Zatorre RJ
通讯作者：
Zatorre RJ
影响因子：
--
作者：
Lachaux, JP;Rudrauf, D;Kahane, P
通讯作者：
Kahane, P
影响因子：
5.3
作者：
Lipski, Witold J.;Alhourani, Ahmad;Richardson, R. Mark
通讯作者：
Richardson, R. Mark
影响因子：
5.3
作者：
Conant, David F.;Bouchard, Kristofer E.;Chang, Edward F.
通讯作者：
Chang, Edward F.