The mood stabilizer lamotrigine produces antidepressant behavioral effects in rats: role of brain-derived neurotrophic factor

The mood stabilizer lamotrigine produces antidepressant behavioral effects in rats: role of brain-derived neurotrophic factor
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情绪稳定剂拉莫三嗪对大鼠产生抗抑郁行为作用:脑源性神经营养因子的作用

DOI:
10.1177/0269881109359102
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发表时间:
2010-12
影响因子:
4.1
通讯作者:
He, Xiaolu
He, Xiaolu
中科院分区:
医学3区
文献类型:
--
作者:
Li, Nanxin;Qi, Xiaoli;Zhang, Yu;He, Shuchang;He, Xiaolu

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抗惊厥药物拉莫三嗪在治疗双相情感障碍患者时已被证明具有很强的抗抑郁作用。然而,到目前为止,在抑郁症动物模型中关于其行为作用的临床前报告很少。
The anticonvulsant drug lamotrigine has been shown to produce strong antidepressant effects in the treatment of patients with bipolar disorder. However, to date there are few preclinical reports on its behavioral actions in animal models of depression or
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