Effect of intensive insulin therapy using a closed-loop glycemic control system in hepatic resection patients: a prospective randomized clinical trial.
Effect of intensive insulin therapy using a closed-loop glycemic control system in hepatic resection patients: a prospective randomized clinical trial.
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DOI：
10.2337/dc08-2107
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发表时间：
2009-08
期刊：
影响因子：
16.2
通讯作者：
Hanazaki K
中科院分区：
文献类型：
--
作者：
Okabayashi T;Nishimori I;Maeda H;Yamashita K;Yatabe T;Hanazaki K
强化胰岛素治疗(IIT)可降低外科重症监护病房患者的发病率和死亡率。这项研究的目的是评估IIT在肝切除患者中使用闭环系统的效果。患者被随机分配到使用闭环系统接受IIT治疗：人工胰腺组(AP组)或使用滑动标度法的常规胰岛素治疗(SS组)。AP组手术部位感染发生率明显低于SS组。AP组患者住院时间明显短于SS组。AP组患者的总住院费用显著低于SS组患者。使用闭环系统的IIT将血糖维持在接近正常的水平，并由于缩短了住院时间，有助于降低SSI的发生率和总住院费用。
Intensive insulin therapy (IIT) reduces morbidity and mortality in patients in surgical intensive care units. The aim of this study is to assess the effect of IIT using a closed-loop system in hepatectomized patients. Patients were randomly assigned to receive IIT using a closed-loop system: an artificial pancreas (AP group) or conventional insulin therapy using the sliding-scale method (SS group). The incidence of surgical-site infection in the AP group was significantly lower than that in the SS group. The length of hospitalization required for patients in the AP group was significantly shorter than that in the SS group. Total hospital costs for patients in the AP group were significantly lower than for patients in the SS group. IIT using a closed-loop system maintained near-normoglycemia and contributed to a reduction in the incidence of SSI and total hospital costs due to shortened hospitalization.
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影响因子：
3
作者：
Alfonso, A;Koops, MK;Vigersky, RA
通讯作者：
Vigersky, RA
DOI：
10.1111/j.1440-1746.2006.04761.x
发表时间：
2007-11-01
影响因子：
4.1
作者：
Togo, Shinji;Matsuo, Kenichi;Shimada, Hiroshi
通讯作者：
Shimada, Hiroshi
影响因子：
6.9
作者：
Ambiru, S.;Kato, A.;Miyazaki, M.
通讯作者：
Miyazaki, M.
影响因子：
5.7
作者：
Yamashita, Koichi;Okabayashi, Takehiro;Hanazaki, Kazuhiro
通讯作者：
Hanazaki, Kazuhiro
影响因子：
158.5
作者：
Van den Berghe, G;Wilmer, A;Bouillon, R
通讯作者：
Bouillon, R