Cellular microbiology: how enteric pathogens socialize with their intestinal host.

Cellular microbiology: how enteric pathogens socialize with their intestinal host.
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细胞微生物学:肠道病原体如何与其肠道宿主交往。

DOI:
10.1097/00005176-199805000-00008
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发表时间:
1998
影响因子:
2.9
通讯作者:
Fasano,A
Fasano,A
中科院分区:
医学4区
文献类型:
--
作者:
Fasano,A

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细胞微生物学是细胞生物学和微生物学的交叉学科。利用微生物病原体来解决细胞生物学中的问题正在产生有前途的应用和优雅的结果。这种研究哺乳动物细胞生物学的新方法最引人注目的例子之一是霍乱弧菌和肠细胞之间的“串扰”。这种相互作用的研究结果为研究肠通透性调节的病理生理学提供了工具,并为通常不能通过肠道吸收的药物和大分子的口服递送开发了替代方法。
A new discipline, cellular microbiology, is emerging at the interface between cell biology and microbiology. The use of microbial pathogens to tackle questions in cell biology is just now yielding promising applications and elegant results. One of the most remarkable examples of this new approach to the study of mammalian cell biology is the “cross talk” betweenVibrio cholerae and intestinal cells. Results of studies on this interaction have provided tools to study the pathophysiology of the regulation of intestinal permeability and to develop alternative approaches for the oral delivery of drugs and macromolecules normally not absorbed through the intestine.
关于霍乱及其芽孢杆菌的演讲
DOI: 10.1136/bmj.2.1235.403
发表时间: 1884
影响因子: --
作者:
R. Koch
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