Auditory neuroimaging with fMRI and PET.

Auditory neuroimaging with fMRI and PET.
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DOI:
10.1016/j.heares.2013.09.009
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发表时间:
2014-01
期刊:
影响因子:
2.8
通讯作者:
Scott, Sophie K.
Scott, Sophie K.
中科院分区:
医学1区
文献类型:
--
作者:
Talavage, Thomas M.;Gonzalez-Castillo, Javier;Scott, Sophie K.

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在过去30年的大部分时间里,听觉感知和语言的研究都得到了加强,甚至是通过使用专门定位中枢反应的功能性神经成像技术来推动的。从使用正电子发射断层扫描(PET)的研究开始,逐渐转向主要使用功能性磁共振成像(fMRI),听觉神经成像极大地促进了我们对大脑区域的组织和响应特性的理解,这些区域对于我们生活的声学世界的感知和沟通至关重要。随着所处理问题的复杂性增加,所采用的技术、实验和分析也变得更加细致和专业化。简要回顾这些调查的历史,为概述和分析这些神经成像方式如何成为理解听觉大脑的更有效工具奠定了基础。最后,我们简要讨论了开放的方法学问题以及听觉神经影像学的潜在临床应用。
For much of the past 30 years, investigations of auditory perception and language have been enhanced or even driven by the use of functional neuroimaging techniques that specialize in localization of central responses. Beginning with investigations using positron emission tomography (PET) and gradually shifting primarily to usage of functional magnetic resonance imaging (fMRI), auditory neuroimaging has greatly advanced our understanding of the organization and response properties of brain regions critical to the perception of and communication with the acoustic world in which we live. As the complexity of the questions being addressed has increased, the techniques, experiments and analyses applied have also become more nuanced and specialized. A brief review of the history of these investigations sets the stage for an overview and analysis of how these neuroimaging modalities are becoming ever more effective tools for understanding the auditory brain. We conclude with a brief discussion of open methodological issues as well as potential clinical applications for auditory neuroimaging.
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