Biomaterials and stem cells for tissue engineering.
Biomaterials and stem cells for tissue engineering.
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DOI：
10.1517/14712598.2013.756468
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发表时间：
2013-04
影响因子：
4.6
通讯作者：
Ma PX
中科院分区：
文献类型：
--
作者：
Zhang Z;Gupte MJ;Ma PX
Organ failure and tissue loss are challenging health issues due to widespread injury, the lack of organs for transplantation, and limitations of conventional artificial implants. The field of tissue engineering aims to provide alternative living substitutes that restore, maintain or improve tissue function. In this paper, a wide range of porous scaffolds are reviewed, with an emphasis on phase separation techniques that generate advantageous nanofibrous 3D scaffolds for stem cell-based tissue engineering applications. In addition, methods for presentation and delivery of bioactive molecules to mimic the properties of stem cell niche are summarized. Recent progress in using these bio-instructive scaffolds to support stem cell differentiation and tissue regeneration is also presented. Stem cells have great clinical potential because of their capability to differentiate into multiple cell types. Biomaterials have served as artificial extracellular environments to regulate stem cell behavior. Biomaterials with various physical, mechanical, and chemical properties can be designed to control stem cell development for regeneration. The research at the interface of stem cell biology and biomaterials has made and will continue to make exciting advances in tissue engineering.
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DOI：
10.1016/j.jconrel.2010.05.035
发表时间：
2010-09-15
期刊：
Journal of controlled release : official journal of the Controlled Release Society
影响因子：
--
作者：
Feng K;Sun H;Bradley MA;Dupler EJ;Giannobile WV;Ma PX
通讯作者：
Ma PX
DOI：
10.1159/000151746
发表时间：
2009
期刊：
Cells, tissues, organs
影响因子：
--
作者：
Brown SE;Tong W;Krebsbach PH
通讯作者：
Krebsbach PH
影响因子：
3.7
作者：
Hu J;Xie C;Ma H;Yang B;Ma PX;Chen YE
通讯作者：
Chen YE
影响因子：
14
作者：
Altman, GH;Diaz, F;Kaplan, DL
通讯作者：
Kaplan, DL
影响因子：
2.8
作者：
CAPLAN, AI
通讯作者：
CAPLAN, AI