Healthy Choices Intervention is Associated with Reductions in Stigma Among Youth Living with HIV in the United States (ATN 129).
Healthy Choices Intervention is Associated with Reductions in Stigma Among Youth Living with HIV in the United States (ATN 129).
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DOI：
10.1007/s10461-020-03071-1
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发表时间：
2021-04
影响因子：
4.4
通讯作者：
Naar S
中科院分区：
文献类型：
--
作者：
Budhwani H;Robles G;Starks TJ;MacDonell KK;Dinaj V;Naar S
考虑到缺乏有效的减少艾滋病毒感染青年（YLWH）的污名干预措施，我们评估了健康选择干预对YLWH中艾滋病毒相关污名的影响。我们分析了来自青少年医学试验网络协议129的数据，这是一项多中心随机对照试验，采用潜在生长曲线模型，采用两个线性斜率估计干预前、干预后16周、28周和52周伯杰污名量表的变化，以及随访期间污名评分的轨迹（N=183）。生长截距的预期值具有统计学显著性（Bintercept=2.53; 95% CI：2.32，2.73; p<0.001），从基线到16周随访的变化差异也具有统计学显著性（Bintercept_slope1=-0.02; 95% CI：-0.04，0.01; p= 0.034）。在随访期间，测量生长的斜率因子的预期值不显著，表明耻辱评分在28至52周期间保持稳定。我们的研究结果值得复制和额外的研究比较这种干预措施的影响，反事实控制。
Considering the lack of validated stigma reduction interventions for youth living with HIV (YLWH), we evaluated effects of the Healthy Choices intervention on HIV-related stigma among YLWH. We analyzed data from the Adolescent Medicine Trials Network protocol 129, multi-site randomized controlled trial, applying latent growth curve modeling with two linear slopes estimating changes in Berger’s Stigma Scale pre-intervention, 16, 28, and 52 weeks post-intervention, as well as the trajectory of stigma scores over the follow-up period (N=183). Expected value for the growth intercept was statistically significant (Bintercept=2.53; 95% CI: 2.32, 2.73; p<.001), as were differences in the change from baseline to 16-week follow-up (Bintercept_slope1=−0.02; 95% CI: −0.04, 0.01; p=.034). Expected value of the slope factor measuring growth over the follow-up period was non-significant suggesting that stigma scores were stable from 28 to 52 weeks. Our findings warrant replication and additional research comparing effects of this intervention to counterfactual controls.
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