Optimism and depression: a new look at social support as a mediator among women at risk for breast cancer.

Optimism and depression: a new look at social support as a mediator among women at risk for breast cancer.
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DOI:
10.1002/pon.3782
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发表时间:
2015-12
期刊:
影响因子:
3.6
通讯作者:
Albano D
Albano D
中科院分区:
医学2区
文献类型:
--
作者:
Garner MJ;McGregor BA;Murphy KM;Koenig AL;Dolan ED;Albano D

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乳腺癌风险是一种与抑郁症相关的慢性压力源。在乳腺癌幸存者中,乐观与较低的抑郁水平有关。然而,据我们所知,目前还没有研究探讨乳腺癌风险女性的乐观和抑郁之间的关系。我们假设,有患乳腺癌风险的女性,乐观程度越高,抑郁程度越低,社会支持会调节这种关系。研究人员从社区招募了199名焦虑程度较高的参与者,并让他们完成抑郁、乐观和社会支持的自我报告测量。参与者根据其乳腺癌家族史进行分组。本研究采用通径分析来检验各组乐观情绪、社会支持与抑郁症状之间的横断面关系。结果表明,有乳腺癌家族史的女性抑郁症状的差异部分可以通过乐观和社会支持的直接路径来解释。通过社会支持从乐观到抑郁症状的间接路径显著(β = - 0.053; 90% CI = -)。099 ~−。011, p = .037)。然而,在没有乳腺癌家族史的个体中,通过社会支持从乐观到抑郁症状的间接途径并不显著。这些结果表明,社会支持在乳腺癌风险女性的乐观和抑郁之间起到部分中介作用。社会支持可能是减少乳腺癌风险妇女抑郁的重要干预目标。
Breast cancer risk is a chronic stressor associated with depression. Optimism is associated with lower levels of depression among breast cancer survivors. However, to our knowledge, no studies have explored the relationship between optimism and depression among women at risk for breast cancer. We hypothesized that women at risk for breast cancer who have higher levels of optimism would report lower levels of depression and that social support would mediate this relationship. Participants (N = 199) with elevated distress were recruited from the community and completed self-report measures of depression, optimism, and social support. Participants were grouped based on their family history of breast cancer. Path analysis was used to examine the cross-sectional relationship between optimism, social support, and depressive symptoms in each group. Results indicated that the variance in depressive symptoms was partially explained through direct paths from optimism and social support among women with a family history of breast cancer. The indirect path from optimism to depressive symptoms via social support was significant (β = −.053; 90% CI = −.099 to −.011, p = .037) in this group. However, among individuals without a family history of breast cancer, the indirect path from optimism to depressive symptoms via social support was not significant. These results suggest that social support partially mediates the relationship between optimism and depression among women at risk for breast cancer. Social support may be an important intervention target to reduce depression among women at risk for breast cancer.
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