Understanding and Harnessing Epithelial‒Mesenchymal Interactions in the Development of Palmoplantar Identity.
Understanding and Harnessing Epithelial‒Mesenchymal Interactions in the Development of Palmoplantar Identity.
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DOI:
10.1016/j.jid.2021.06.016
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发表时间:
2022-03
期刊:
影响因子:
--
通讯作者:
Garza LA
中科院分区:
文献类型:
--
作者:
Tsai J;Rostom M;Garza LA
Palmoplantar skin has several unique characteristics such as increased thickness, high resilience, hypopigmentation, and lack of hair follicles. The establishment of palmoplantar identity occurs through keratinocyte-fibroblast interactions, with keratin 9 expression and Wnt signaling playing key roles. Understanding how palmoplantar features develop may help efforts to reproduce them at both palmoplantar and non-palmoplantar body sites.
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影响因子:
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DOI:
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