The MetaCyc database of metabolic pathways and enzymes and the BioCyc collection of pathway/genome databases.
The MetaCyc database of metabolic pathways and enzymes and the BioCyc collection of pathway/genome databases.
复制标题
DOI：
10.1093/nar/gkp875
复制
发表时间：
2010-01
影响因子：
14.9
通讯作者：
Karp PD
中科院分区：
文献类型：
--
作者：
Caspi R;Altman T;Dale JM;Dreher K;Fulcher CA;Gilham F;Kaipa P;Karthikeyan AS;Kothari A;Krummenacker M;Latendresse M;Mueller LA;Paley S;Popescu L;Pujar A;Shearer AG;Zhang P;Karp PD
Metacyc数据库（Metacyc.org）是来自生命的所有领域的代谢途径和酶的全面且可自由获取的资源。 Metacyc中的途径是实验确定的小分子代谢途径，并通过主要科学文献进行策划。 Metacyc拥有1400多个途径，是目前可用的最大代谢途径集合。途径反应与一种或多种特征良好的酶有关，并用评论，证据代码和文献引用了途径和酶。 Biocyc（Biocyc.org）是500多个有机体特异性途径/基因组数据库（PGDB）的集合。每个Biocyc PGDB都包含一个有机体的完整基因组和预测的代谢网络。该网络由使用Metacyc作为参考的途径工具软件预测，由代谢物，酶，反应和代谢途径组成。 Biocyc PGDB还包含其他功能，例如预测的操纵子，传输系统和孔洞填充剂。 BioCyc网站提供了几种用于分析PGDB的工具，包括OMICS观众，可以在两个不同的基因组尺度图和比较分析的工具上可视化OMICS数据集。 SRI生成的Bioocyc PGDB均由对有机体的代谢，法规和基因组相关信息感兴趣的任何一方采用。
The MetaCyc database (MetaCyc.org) is a comprehensive and freely accessible resource for metabolic pathways and enzymes from all domains of life. The pathways in MetaCyc are experimentally determined, small-molecule metabolic pathways and are curated from the primary scientific literature. With more than 1400 pathways, MetaCyc is the largest collection of metabolic pathways currently available. Pathways reactions are linked to one or more well-characterized enzymes, and both pathways and enzymes are annotated with reviews, evidence codes, and literature citations. BioCyc (BioCyc.org) is a collection of more than 500 organism-specific Pathway/Genome Databases (PGDBs). Each BioCyc PGDB contains the full genome and predicted metabolic network of one organism. The network, which is predicted by the Pathway Tools software using MetaCyc as a reference, consists of metabolites, enzymes, reactions and metabolic pathways. BioCyc PGDBs also contain additional features, such as predicted operons, transport systems, and pathway hole-fillers. The BioCyc Web site offers several tools for the analysis of the PGDBs, including Omics Viewers that enable visualization of omics datasets on two different genome-scale diagrams and tools for comparative analysis. The BioCyc PGDBs generated by SRI are offered for adoption by any party interested in curation of metabolic, regulatory, and genome-related information about an organism.
登录
查看更多内容
影响因子：
3.2
作者：
Aanensen, David M.;Mavroldi, Angeliki;Spratt, Brian G.
通讯作者：
Spratt, Brian G.
影响因子：
14.9
作者：
Christie, KR;Weng, S;Cherry, JM
通讯作者：
Cherry, JM
影响因子：
7.4
作者：
Mueller, LA;Zhang, PF;Rhee, SY
通讯作者：
Rhee, SY
影响因子：
4.4
作者：
Valdés J;Veloso F;Jedlicki E;Holmes D
通讯作者：
Holmes D
影响因子：
5.8
作者：
Urbanczyk-Wochniak, Ewa;Sumner, Lloyd W.
通讯作者：
Sumner, Lloyd W.