Advancing Strongyloides omics data: bridging the gap with Caenorhabditis elegans.
Advancing Strongyloides omics data: bridging the gap with Caenorhabditis elegans.
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DOI：
10.1098/rstb.2022.0437
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发表时间：
2024-01-15
影响因子：
6.3
通讯作者：
Hunt, Vicky
中科院分区：
文献类型：
--
作者：
Al-Jawabreh, Reem;Lastik, Dominika;Mckenzie, Darrin;Reynolds, Kieran;Suleiman, Mona;Mousley, Angela;Atkinson, Louise;Hunt, Vicky
在线虫中，自由生活的模式生物秀丽隐杆线虫拥有最先进的高质量组学数据组合。寄生线虫，包括类圆线虫属，然而，却落在后面。而C.秀丽线虫仍然是最易处理的线虫，并且显著地推进了我们对线虫生物学的许多方面的理解，C.线虫不适合作为研究寄生性的替代系统，重要的是我们要改进可用于寄生线虫物种的组学资源。在这里，我们回顾了可用于类圆线虫属的组学数据。并将可用资源与C的可用资源进行比较。线虫和其他寄生线虫。C.线虫组学为改进类圆线虫组学主导的研究提供了蓝图。我们提出了未来研究的优先领域，这将为组学资源和技术的扩展铺平道路。这篇文章是Theo Murphy会议议题“类圆线虫：无虫种群的组学”的一部分。
Among nematodes, the free-living model organism Caenorhabditis elegans boasts the most advanced portfolio of high-quality omics data. The resources available for parasitic nematodes, including Strongyloides spp., however, are lagging behind. While C. elegans remains the most tractable nematode and has significantly advanced our understanding of many facets of nematode biology, C. elegans is not suitable as a surrogate system for the study of parasitism and it is important that we improve the omics resources available for parasitic nematode species. Here, we review the omics data available for Strongyloides spp. and compare the available resources to those for C. elegans and other parasitic nematodes. The advancements in C. elegans omics offer a blueprint for improving omics-led research in Strongyloides. We suggest areas of priority for future research that will pave the way for expansions in omics resources and technologies. This article is part of the Theo Murphy meeting issue ‘Strongyloides: omics to worm-free populations’.
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DOI：
10.1098/rstb.2022.0447
发表时间：
2024-01-15
影响因子：
6.3
作者：
Tiberti, Natalia;Manfredi, Marcello;Piubelli, Chiara;Buonfrate, Dora
通讯作者：
Buonfrate, Dora
影响因子：
4.9
作者：
Bao W;Kojima KK;Kohany O
通讯作者：
Kohany O
影响因子：
2.4
作者：
Analia Repetto, Silvia;Quarroz Braghini, Juan;Ruybal, Paula
通讯作者：
Ruybal, Paula
影响因子：
1.3
作者：
Anderson, J.;Upadhayay, R.;Anderson, T. J. C.
通讯作者：
Anderson, T. J. C.
影响因子：
4.6
作者：
Suleiman, Mona;Kounosu, Asuka;Murcott, Ben;Dayi, Mehmet;Pawluk, Rebecca;Yoshida, Akemi;Viney, Mark;Kikuchi, Taisei;Hunt, Vicky L.
通讯作者：
Hunt, Vicky L.