Associations between maternal pre-pregnancy body mass index and neonatal neurobehavior in infants born before 30 weeks gestation.
Associations between maternal pre-pregnancy body mass index and neonatal neurobehavior in infants born before 30 weeks gestation.
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DOI:
10.1038/s41372-021-01308-y
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发表时间:
2022-04
影响因子:
2.9
通讯作者:
Lester, Barry M.
中科院分区:
文献类型:
--
作者:
Nosavan, Nina P.;Smith, Lynne M.;Dansereau, Lynne M.;Roberts, Mary B.;Hofheimer, Julie A.;Carter, Brian S.;Helderman, Jennifer B.;McGowan, Elisabeth C.;Neal, Charles R.;Pastyrnak, Steve;Della Grotta, Sheri A.;O'Shea, T. Michael;Lester, Barry M.
To examine the relationship between maternal pre-pregnancy body mass index (BMI) and neonatal neurobehavior in very premature infants. Multi-center prospective observational study of 664 very preterm infants with 227 born to obese mothers. The NICU Network Neurobehavioral Scale (NNNS) assessed neurobehavior at NICU discharge. Elevated BMI combined with infection increased the odds of having the most poorly regulated NNNS profile by 1.9 times per BMI SD. Infants born to mothers with elevated BMI in combination with: infection had poorer self-regulation, chorioamnionitis had increased asymmetrical reflexes, diabetes had poorer attention and low SES required more handling. Maternal pre-pregnancy BMI alone did not affect short-term neonatal neurobehavior in infants born before 30 weeks gestation. Infants born to mothers with elevated pre-pregnancy weight in addition to infections, diabetes, or socioeconomic adversity demonstrated increased risk of having the most poorly regulated NNNS profile and deficits in multiple domains.
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DOI:
10.1016/j.jpeds.2017.02.064
发表时间:
2017-08
期刊:
The Journal of pediatrics
影响因子:
--
作者:
Jensen ET;van der Burg JW;O'Shea TM;Joseph RM;Allred EN;Heeren T;Leviton A;Kuban KCK;Extremely Low Gestational Age Newborns Study Investigators
通讯作者:
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影响因子:
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DOI:
10.1152/ajpregu.00310.2010
发表时间:
2010-09-01
影响因子:
2.8
作者:
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通讯作者:
Friedman, Jacob E.
影响因子:
8
作者:
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Leviton, Alan