The front line of defence: a meta-analysis of apoplastic proteases in plant immunity.
The front line of defence: a meta-analysis of apoplastic proteases in plant immunity.
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DOI：
10.1093/jxb/eraa602
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发表时间：
2021-04-13
影响因子：
6.9
通讯作者：
van der Hoorn RAL
中科院分区：
文献类型：
--
作者：
Godson A;van der Hoorn RAL
分泌的蛋白酶在防御的前线发挥作用，在抗病性中发挥着关键作用。然而，质外体免疫蛋白酶的标准并不总是被定义和遵循。在这里，我们严格审查了 46 种在植物防御中发挥作用的质外体蛋白酶。我们发现大多数质外体免疫蛋白酶是在感染时诱导产生的，并且 17 种蛋白酶是免疫反应的遗传所需。大多数蛋白酶的蛋白水解活性已得到证实，但很少表明其是生物功能所必需的，并且蛋白酶的质外体定位可以是主观的和动态的。仅针对半胱氨酸和丝氨酸蛋白酶描述了病原体衍生的抑制剂，并且很少研究作用于免疫蛋白酶的选择压力。我们讨论了这些蛋白酶介导植物免疫的六种不同机制，并总结了未来研究的挑战。该荟萃分析讨论了 46 种已知的质外体免疫蛋白酶的质外体位置、蛋白酶活性及其对免疫的贡献，并确定了蛋白酶在免疫中发挥作用的六种不同机制。
Secreted proteases act at the front line of defence and play pivotal roles in disease resistance. However, the criteria for apoplastic immune proteases are not always defined and followed. Here, we critically reviewed 46 apoplastic proteases that function in plant defence. We found that most apoplastic immune proteases are induced upon infection, and 17 proteases are genetically required for the immune response. Proteolytic activity has been confirmed for most of the proteases but is rarely shown to be required for biological function, and the apoplastic location of proteases can be subjective and dynamic. Pathogen-derived inhibitors have only been described for cysteine and serine proteases, and the selection pressure acting on immune proteases is rarely investigated. We discuss six different mechanisms by which these proteases mediate plant immunity and summarize the challenges for future research. This meta-analysis discusses 46 known apoplastic immune proteases for their apoplastic location, protease activity, and their contribution to immunity, and identifies six different mechanisms for proteases acting in immunity.
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影响因子：
16.6
作者：
Clark K;Franco JY;Schwizer S;Pang Z;Hawara E;Liebrand TWH;Pagliaccia D;Zeng L;Gurung FB;Wang P;Shi J;Wang Y;Ancona V;van der Hoorn RAL;Wang N;Coaker G;Ma W
通讯作者：
Ma W
影响因子：
3.7
作者：
Ekchaweng K;Evangelisti E;Schornack S;Tian M;Churngchow N
通讯作者：
Churngchow N
DOI：
10.1186/s12284-014-0009-2
发表时间：
2014-12
期刊：
Rice (New York, N.Y.)
影响因子：
--
作者：
Alam MM;Nakamura H;Ichikawa H;Miyao A;Hirochika H;Kobayashi K;Yamaoka N;Nishiguchi M
通讯作者：
Nishiguchi M
影响因子：
5.6
作者：
Balakireva AV;Zamyatnin AA
通讯作者：
Zamyatnin AA
影响因子：
5.6
作者：
Figueiredo A;Monteiro F;Sebastiana M
通讯作者：
Sebastiana M