Traditional Medicinal Plants as a Source of Antituberculosis Drugs: A System Review.

Traditional Medicinal Plants as a Source of Antituberculosis Drugs: A System Review.
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传统药用植物作为抗结核药物的来源:系统回顾

DOI:
10.1155/2021/9910365
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发表时间:
2021
影响因子:
--
通讯作者:
Sun Z
Sun Z
中科院分区:
生物学3区
文献类型:
--
作者:
Xu Y;Liang B;Kong C;Sun Z

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药用植物是世界各地不同传统医学体系中不同东方配方的主要成分。药用植物作为一种新兴的药物来源,具有抗结核的特性,激发了药剂师基于其活性成分或半代谢产物开发新药的研究。本文从植物学分类和抗结核活性两方面对抗结核药用植物进行了筛选。将获得的抗TB药用植物分为三个不同的类别,即,对159种植物共335个分离化合物进行了严格的研究,其中131种植物的粗提物显示出抗结核活性,27种植物在文献中具有传统治疗师的处方。我们对药用植物的系统分析有助于发现新的和更有效的抗结核药物。
Medicinal plants are the chief components in the different oriental formulations in different traditional medical systems worldwide. As a thriving source of medicine, the medicinal plants with antituberculosis (TB) properties inspire the pharmacists to develop new drugs based on their active components or semimetabolites. In the present review, the anti-TB medicinal plants were screened from the scientific literatures, based on the botanical classification and the anti-TB activity. The obtained anti-TB medicinal plants were categorized into three different categories, viz., 159 plants critically examined with a total 335 isolated compounds, 131 plants with their crude extracts showing anti-TB activity, and 27 plants in literature with the prescribed formula by the traditional healers. Our systemic analysis on the medicinal plants can assist the discovery of novel and more efficacious anti-TB drugs.
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发表时间: 2005-01-01
影响因子: 2
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