Distribution of ossified spinal lesions in patients with severe ossification of the posterior longitudinal ligament and prediction of ossification at each segment based on the cervical OP index classification: a multicenter study (JOSL CT study).
Distribution of ossified spinal lesions in patients with severe ossification of the posterior longitudinal ligament and prediction of ossification at each segment based on the cervical OP index classification: a multicenter study (JOSL CT study).
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DOI：
10.1186/s12891-018-2009-7
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发表时间：
2018-04-05
影响因子：
2.3
通讯作者：
Kawaguchi Y
中科院分区：
文献类型：
--
作者：
Hirai T;Yoshii T;Nagoshi N;Takeuchi K;Mori K;Ushio S;Iwanami A;Yamada T;Seki S;Tsuji T;Fujiyoshi K;Furukawa M;Nishimura S;Wada K;Furuya T;Matsuyama Y;Hasegawa T;Takeshita K;Kimura A;Abematsu M;Haro H;Ohba T;Watanabe M;Katoh H;Watanabe K;Ozawa H;Kanno H;Imagama S;Ando K;Fujibayashi S;Koda M;Yamazaki M;Matsumoto M;Nakamura M;Okawa A;Kawaguchi Y
颈椎后纵韧带骨化症（OPLL）患者中，众所周知，胸椎骨化病变常与颈椎病变并存，可引起严重的脊髓病。然而，胸椎和腰椎各节段 OPLL 的患病率尚不清楚。本研究的目的是调查放射学诊断为颈椎 OPLL 的患者胸腰椎各节段发生 OPLL 的频率，并确定最有可能发生骨化的脊柱节段。数据收集自日本 20 个机构。包括 322 名诊断为颈椎后纵韧带骨化 (OPLL) 的患者。 OPLL 指数（OP 指数）定义为存在 OPLL 的椎体和椎间盘水平的总和，用于确定疾病的严重程度。 OP指数≥20被定义为严重OPLL。计算胸椎和腰椎各节段 OPLL 的患病率。女性比男性更容易出现胸腰椎骨化病变。严重后纵韧带骨化（OPLL）在女性中明显高于男性（20% vs. 4.5%）。对于胸椎 OPLL，男性和女性最常受影响的是 T1 节段，其次分别是男性和女性的 T1/2 和 T3/4 椎间水平。男性重度OPLL的骨化病变常见于颈胸椎和胸腰椎交界处周围的椎间和椎体水平，而女性重度OPLL的OPLL更广泛地分布在胸椎。胸腰椎 OPLL 最常发生在男性的 T1 和女性的 T3/4。在严重的OPLL病例中，虽然男性的颈胸椎和胸腰椎交界处周围的椎间和椎体水平经常看到骨化病变，但女性的胸椎中可以观察到更广泛的OPLL。
In patients with ossification of the posterior longitudinal ligament (OPLL) in the cervical spine, it is well known that the thoracic ossified lesions often coexist with the cervical lesions and can cause severe myelopathy. However, the prevalence of OPLL at each level of the thoracic and lumbar spinal segments is unknown. The aims of this study were to investigate how often OPLL occurs at each level in the thoracolumbar spine in patients with a radiological diagnosis of cervical OPLL and to identify the spinal levels most likely to develop ossification. Data were collected from 20 institutions in Japan. Three hundred and twenty-two patients with a diagnosis of cervical OPLL were included. The OPLL index (OP index), defined as the sum of the vertebral body and intervertebral disc levels where OPLL is present, was used to determine disease severity. An OP index ≥20 was defined as severe OPLL. The prevalence of OPLL at each level of the thoracic and lumbar spinal segments was calculated. Women were more likely to have ossified lesions in the thoracolumbar spine than men. Severe OPLL was significantly more common in women than in men (20% vs. 4.5%). For thoracic vertebral OPLL, the most frequently affected was the T1 segment in both men and women, followed by the T1/2 and T3/4 intervertebral levels in men and women, respectively. Ossified lesions were frequently seen at the intervertebral and vertebral levels around the cervicothoracic and thoracolumbar junctions in men with severe OPLL, whereas OPLL was more diffusely distributed in the thoracic spine in women with severe OPLL. Thoracolumbar OPLL occurred most often at T1 in men and at T3/4 in women. In severe OPLL cases, although ossified lesions were frequently seen at the intervertebral and vertebral levels around the cervicothoracic and thoracolumbar junctions in men, OPLL could be observed more diffusely in the thoracic spine in women.
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脊柱后纵韧带的宫颈骨化患者中骨上韧带的骨化的患病率和分布：一项基于CT的多中心横截面研究。
影响因子：
2.3
作者：
Mori K;Yoshii T;Hirai T;Iwanami A;Takeuchi K;Yamada T;Seki S;Tsuji T;Fujiyoshi K;Furukawa M;Nishimura S;Wada K;Koda M;Furuya T;Matsuyama Y;Hasegawa T;Takeshita K;Kimura A;Abematsu M;Haro H;Ohba T;Watanabe M;Katoh H;Watanabe K;Ozawa H;Kanno H;Imagama S;Ito Z;Fujibayashi S;Yamazaki M;Matsumoto M;Nakamura M;Okawa A;Kawaguchi Y
通讯作者：
Kawaguchi Y
影响因子：
3
作者：
Sakai, Kenichiro;Okawa, Atsushi;Shinomiya, Kenichi
通讯作者：
Shinomiya, Kenichi
影响因子：
3
作者：
Park, Jeong Yoon;Chin, Dong Kyu;Cho, Yong Eun
通讯作者：
Cho, Yong Eun
影响因子：
3
作者：
Fujimori, Takahito;Watabe, Tadashi;Oda, Takenori
通讯作者：
Oda, Takenori
纵向韧带宫颈骨化患者的整个脊柱中骨化病变的患病率和分布（JOSL CT研究）。
影响因子：
3.7
作者：
Hirai T;Yoshii T;Iwanami A;Takeuchi K;Mori K;Yamada T;Wada K;Koda M;Matsuyama Y;Takeshita K;Abematsu M;Haro H;Watanabe M;Watanabe K;Ozawa H;Kanno H;Imagama S;Fujibayashi S;Yamazaki M;Matsumoto M;Nakamura M;Okawa A;Kawaguchi Y
通讯作者：
Kawaguchi Y