Genomic encyclopedia of bacteria and archaea: sequencing a myriad of type strains.
Genomic encyclopedia of bacteria and archaea: sequencing a myriad of type strains.
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DOI：
10.1371/journal.pbio.1001920
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发表时间：
2014-08
期刊：
影响因子：
9.8
通讯作者：
Klenk HP
中科院分区：
文献类型：
--
作者：
Kyrpides NC;Hugenholtz P;Eisen JA;Woyke T;Göker M;Parker CT;Amann R;Beck BJ;Chain PS;Chun J;Colwell RR;Danchin A;Dawyndt P;Dedeurwaerdere T;DeLong EF;Detter JC;De Vos P;Donohue TJ;Dong XZ;Ehrlich DS;Fraser C;Gibbs R;Gilbert J;Gilna P;Glöckner FO;Jansson JK;Keasling JD;Knight R;Labeda D;Lapidus A;Lee JS;Li WJ;Ma J;Markowitz V;Moore ER;Morrison M;Meyer F;Nelson KE;Ohkuma M;Ouzounis CA;Pace N;Parkhill J;Qin N;Rossello-Mora R;Sikorski J;Smith D;Sogin M;Stevens R;Stingl U;Suzuki K;Taylor D;Tiedje JM;Tindall B;Wagner M;Weinstock G;Weissenbach J;White O;Wang J;Zhang L;Zhou YG;Field D;Whitman WB;Garrity GM;Klenk HP
这份手稿呼吁国际社会共同努力，从所有古菌和细菌类型菌株的基因组序列中生成一个全面的目录。微生物掌握着生命的关键。它们掌握着我们过去的秘密（作为最早生命形式的后代）和我们未来的前景（当我们挖掘它们的基因来解决地球上一些最紧迫的问题，从全球变暖到抗生素耐药性）。然而，20 多年来，在 30,000 多个基因组项目中，这种零敲碎打的方法已经确定了微生物遗传多样性研究的努力，但这种方法可能会浪费这一承诺。这些努力覆盖了不到 20% 的培养古菌和细菌物种多样性，仅占已知原核生物多样性的 15%。在此，我们呼吁资助一项系统性工作，通过对每个物种的典型菌株进行测序（如有）并提供有效公布的名称（目前约为 11,000 个），从而生成所有培养细菌和古细菌的综合基因组目录。这项工作将为我们星球的遗传多样性提供前所未有的覆盖水平，允许大规模发现新的基因和功能，并提高对环境中微生物进化和功能的了解。
This manuscript calls for an international effort to generate a comprehensive catalog from genome sequences of all the archaeal and bacterial type strains. Microbes hold the key to life. They hold the secrets to our past (as the descendants of the earliest forms of life) and the prospects for our future (as we mine their genes for solutions to some of the planet's most pressing problems, from global warming to antibiotic resistance). However, the piecemeal approach that has defined efforts to study microbial genetic diversity for over 20 years and in over 30,000 genome projects risks squandering that promise. These efforts have covered less than 20% of the diversity of the cultured archaeal and bacterial species, which represent just 15% of the overall known prokaryotic diversity. Here we call for the funding of a systematic effort to produce a comprehensive genomic catalog of all cultured Bacteria and Archaea by sequencing, where available, the type strain of each species with a validly published name (currently∼11,000). This effort will provide an unprecedented level of coverage of our planet's genetic diversity, allow for the large-scale discovery of novel genes and functions, and lead to an improved understanding of microbial evolution and function in the environment.
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影响因子：
64.8
作者：
通讯作者：
--
影响因子：
5.9
作者：
FAITH, DP
通讯作者：
FAITH, DP
DOI：
10.1126/science.1183605
发表时间：
2010-05-21
期刊：
Science (New York, N.Y.)
影响因子：
--
作者：
Human Microbiome Jumpstart Reference Strains Consortium;Nelson KE;Weinstock GM;Highlander SK;Worley KC;Creasy HH;Wortman JR;Rusch DB;Mitreva M;Sodergren E;Chinwalla AT;Feldgarden M;Gevers D;Haas BJ;Madupu R;Ward DV;Birren BW;Gibbs RA;Methe B;Petrosino JF;Strausberg RL;Sutton GG;White OR;Wilson RK;Durkin S;Giglio MG;Gujja S;Howarth C;Kodira CD;Kyrpides N;Mehta T;Muzny DM;Pearson M;Pepin K;Pati A;Qin X;Yandava C;Zeng Q;Zhang L;Berlin AM;Chen L;Hepburn TA;Johnson J;McCorrison J;Miller J;Minx P;Nusbaum C;Russ C;Sykes SM;Tomlinson CM;Young S;Warren WC;Badger J;Crabtree J;Markowitz VM;Orvis J;Cree A;Ferriera S;Fulton LL;Fulton RS;Gillis M;Hemphill LD;Joshi V;Kovar C;Torralba M;Wetterstrand KA;Abouellleil A;Wollam AM;Buhay CJ;Ding Y;Dugan S;FitzGerald MG;Holder M;Hostetler J;Clifton SW;Allen-Vercoe E;Earl AM;Farmer CN;Liolios K;Surette MG;Xu Q;Pohl C;Wilczek-Boney K;Zhu D
通讯作者：
Zhu D
影响因子：
14.9
作者：
Pagani I;Liolios K;Jansson J;Chen IM;Smirnova T;Nosrat B;Markowitz VM;Kyrpides NC
通讯作者：
Kyrpides NC
影响因子：
--
作者：
Goeker, Markus;Klenk, Hans-Peter
通讯作者：
Klenk, Hans-Peter