Obesity and Central Adiposity in Japanese Immigrants: Role of the Western Dietary Pattern
Obesity and Central Adiposity in Japanese Immigrants: Role of the Western Dietary Pattern
复制标题
日本移民的肥胖和中心性肥胖：西方饮食模式的作用
作者：
Sandra R. G. Ferreira;Daniel D G Lerario;S. Gimeno;A. Sañudo;L. Franco
我们在第一代和第二代日本-巴西人群的代表性样本（n=530，年龄40-79岁）中研究了营养因素与体脂沉积的相关性，这些人群提交了标准化问卷，包括营养数据，临床检查和实验室程序。饮食数据进行了比较组之间的定义为肥胖或中心性肥胖的存在。通过多元线性回归分析了体重指数或腰围（因变量）与能量和营养素摄入量（主要关注的暴露量）的关系，并对性别、年龄、体力活动和世代进行了调整。肥胖组和中心性肥胖组的脂肪能量消耗比例高于非肥胖组和非中心性肥胖组（p<0.05），碳水化合物能量消耗比例低于非肥胖组（p<0.05）。按世代分层，第二代比第一代以脂肪形式吸收更多的能量（p<0.05）。在回归模型中，蛋白质摄入量是唯一与体重指数显著相关的变量。用腰围代替体重指数，男性和蛋白质摄入量被证明是中心性肥胖的独立预测因子。当服用第二代时，总能量摄入量和所有常量营养素摄入量与体重指数显著相关（p<0.05），但只有蛋白质摄入量预测腰围。我们推测，日本-巴西人，遗传上容易出现胰岛素抵抗，当暴露于不利的环境将表达一些代谢紊乱。有害的饮食模式可能导致体重增加，与腹部脂肪沉积有关，特别是富含蛋白质的饮食，并反映在他们的腰围上。腹内脂肪可能引发胰岛素抵抗，这可以解释日本巴西人糖尿病、血脂异常和高血压患病率的增加。
We examined the association of nutritional factors with body fat deposition in a representative sample (n=530, aged 40-79 years) of first and second-generation Japanese-Brazilian population who was submitted to standardized questionnaires, including nutritional data, clinical examination and laboratory procedures. Dietary data were compared between groups of subjects defined by the presence of obesity or central adiposity. Associations of body mass index or waist circumference (dependent variables) with energy and nutrient intakes (main exposure of interest) were analyzed by multiple linear regression, with adjustment for gender, age, physical activity and generation. Groups of obese subjects and those with central adiposity consumed higher proportions of energy as fat and lower as carbohydrate than those without obesity and central adiposity (p<0.05). Stratifying by generation, second-generation was shown to take more energy as fat than the first-generation (p<0.05). In the regression models, protein intake was the only variable significantly associated with body mass index. Replacing body mass index by the waist circumference, male sex and protein intake were shown to be independent predictors of central adiposity. When second-generation was taken, total energy intake and all macronutrient intakes became significantly associated with body mass index (p<0.05) but only protein intake predicted waist circumference. We speculate that Japanese-Brazilians, genetically prone to insulin resistance, when exposed to unfavorable environment will express a number of metabolic disturbances. A deleterious dietary pattern may contribute to weight gain, was associated with abdominal fat deposition in particular a protein-rich diet, and reflected by their waist circumference. Intra-abdominal fat could be triggering insulin resistance, which would explain the increased prevalence rates of diabetes, dyslipidemia and hypertension seen in Japanese-Brazilians.
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影响因子：
5
作者：
WILLETT, W;STAMPFER, MJ
通讯作者：
STAMPFER, MJ
影响因子：
7.1
作者：
TSUNEHARA, CH;LEONETTI, DL;FUJIMOTO, WY
通讯作者：
FUJIMOTO, WY
内脏脂肪肥胖和发病率：日裔美国男性和女性的 NIDDM 和动脉粥样硬化风险。
影响因子：
4.9
作者：
Fujimoto,WY;Newell-Morris,LL;Grote,M;Bergstrom,RW;Shuman,WP
通讯作者：
Shuman,WP
影响因子：
7.1
作者：
COLDITZ, GA;MANSON, JE;SPEIZER, FE
通讯作者：
SPEIZER, FE