TAM receptors and their ligand-mediated activation: Role in atherosclerosis.
TAM receptors and their ligand-mediated activation: Role in atherosclerosis.
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TAM受体及其配体介导的激活：在动脉粥样硬化中的作用。
DOI：
10.1016/bs.ircmb.2020.09.001
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发表时间：
2020
影响因子：
--
通讯作者：
Kasikara C
中科院分区：
文献类型：
--
作者：
Cai B;Kasikara C
TAM family tyrosine kinase receptors including Tyro3, Axl, and MerTK are the key efferocytosis receptors presenting on antigen-presenting cell that mediate the clearance of apoptotic cells. They are thought to regulate inflammatory diseases by modulating inflammatory response and efferocytosis. Recent studies have revealed novel roles of TAM receptors in the biosynthesis of specialized pro-resolving mediators (SPMs) and inflammation resolution. In this chapter, we discuss the central roles of TAM signaling in atherosclerosis focusing on their regulation in efferocytosis and inflammation resolution and highlight the unique therapeutic potential of SPMs in blocking the progression of atherosclerosis.
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影响因子：
29
作者：
Cai, Bishuang;Dongiovanni, Paola;Tabas, Ira
通讯作者：
Tabas, Ira
影响因子：
7.3
作者：
Geng K;Kumar S;Kimani SG;Kholodovych V;Kasikara C;Mizuno K;Sandiford O;Rameshwar P;Kotenko SV;Birge RB
通讯作者：
Birge RB
影响因子：
5.2
作者：
Lemke G;Burstyn-Cohen T
通讯作者：
Burstyn-Cohen T
影响因子：
37.8
作者：
Kojima Y;Weissman IL;Leeper NJ
通讯作者：
Leeper NJ
影响因子：
20.1
作者：
DeBerge M;Yeap XY;Dehn S;Zhang S;Grigoryeva L;Misener S;Procissi D;Zhou X;Lee DC;Muller WA;Luo X;Rothlin C;Tabas I;Thorp EB
通讯作者：
Thorp EB