Neuromodulation of associative and organizational plasticity across the life span: Empirical evidence and neurocomputational modeling
Neuromodulation of associative and organizational plasticity across the life span: Empirical evidence and neurocomputational modeling
复制标题
整个生命周期中联想和组织可塑性的神经调节：经验证据和神经计算模型
DOI：
10.1016/j.neubiorev.2006.06.004
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发表时间：
2006
影响因子：
8.2
通讯作者：
U. Lindenberger
中科院分区：
文献类型：
--
作者：
Shu;Yvonne Brehmer;Y. Shing;M. Werkle;U. Lindenberger
发育可塑性是允许人类和其他生物体修改和适应环境和经验影响的关键机制。因此，行为和神经元可塑性之间的互惠共建性相互作用在调节整个生命周期的神经行为发育中起着重要作用。这篇评论的重点是行为和神经元的证据寿命差异的联想记忆可塑性和可塑性的功能组织的认知和皮层过程，以及多巴胺能系统在调节这种可塑性的作用。特别注意的是神经计算模型，有助于探索神经元和行为可塑性的神经调制的寿命差异。从这些模型的模拟结果表明，寿命的神经调节机制的功效的变化可能形状的联想记忆可塑性和神经认知过程的功能组织，通过影响神经元信号传输的保真度，这对神经认知表征的独特性和分布式神经编码的功效的后果。
Developmental plasticity is the key mechanism that allows humans and other organisms to modify and adapt to contextual and experiential influences. Thus, reciprocal co-constructive interactions between behavioral and neuronal plasticity play important roles in regulating neurobehavioral development across the life span. This review focuses on behavioral and neuronal evidence of lifespan differences in associative memory plasticity and plasticity of the functional organization of cognitive and cortical processes, as well as the role of the dopaminergic system in modulating such plasticity. Special attention is given to neurocomputational models that help exploring lifespan differences in neuromodulation of neuronal and behavioral plasticity. Simulation results from these models suggest that lifespan changes in the efficacy of neuromodulatory mechanisms may shape associative memory plasticity and the functional organization of neurocognitive processes by affecting the fidelity of neuronal signal transmission, which has consequences for the distinctiveness of neurocognitive representations and the efficacy of distributed neural coding.
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DOI：
--
发表时间：
1998
期刊：
Annals of the New York Academy of Sciences.
影响因子：
--
作者：
Richardson,GA
通讯作者：
Richardson,GA
影响因子：
17.7
作者：
Diamond, A;Briand, L;Gehlbach, L
通讯作者：
Gehlbach, L
影响因子：
5.4
作者：
COHEN, JD;SERVANSCHREIBER, D
通讯作者：
SERVANSCHREIBER, D
影响因子：
3.7
作者：
Schaie, KW;Maitland, SB;Intrieri, RC
通讯作者：
Intrieri, RC
DOI：
10.1073/pnas.0405148101
发表时间：
2004-08-31
影响因子：
11.1
作者：
Park, DC;Polk, TA;Smith, MR
通讯作者：
Smith, MR