Canonical Wnt signaling: high-throughput RNAi widens the path.
Canonical Wnt signaling: high-throughput RNAi widens the path.
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DOI：
10.1186/gb-2005-6-9-231
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发表时间：
2005
期刊：
影响因子：
12.3
通讯作者：
Brown AM
中科院分区：
文献类型：
--
作者：
Brown AM
Although Wnt signaling has been the subject of extensive genetic analysis in the past, some 200 genes have now been identified as candidate modulators of this pathway by a recent study using high-throughput RNAi screening. The canonical Wnt signaling pathway is highly conserved in evolution, widely used throughout animal development, and frequently hyperactive in cancer. Although Wnt signaling has been the subject of extensive genetic analysis in the past, some 200 genes have now been identified as candidate modulators of this pathway by a recent study using high-throughput RNAi screening.
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